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US 2021/0260579 A1Published application
Plasma separating microfluidic device
AssigneeCapitainer AB
InventorsNiclas ROXHED, Göran STEMME, Gabriel LENK, Wouter VAN DER WIJNGAART, Jonas HANSSON
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Abstract
A capillary driven microfluidic device with blood plasma separation means that can be used to separate, meter and transfer a blood sample. The blood separation means can be arranged as a capillary pump by the configuration of a porous membrane and the microfluidic device.
Claims9
1-11. (canceled)
A method of preparing and transporting a sample from whole blood comprising the steps of:
- (i) arranging in a microfluidic device, a porous blood plasma separating membrane in an acute angle with a hydrophilic surface of a support structure;
- (ii) applying at least 30 μl whole blood to an upper surface of the membrane and admitting separation of plasma through the membrane;
- (iii) admitting a wedge-shaped space between the membrane and the support structure gradually be filled with separated plasma;
- and
- (iv) filling a capillary channel in fluid communication with said space and metering a defined volume of separated plasma.
2 more elements
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Dependencies are inferred from the claim text.