Brain drug delivery system and method
AssigneePostsurgical Therapeutics, Inc.
InventorSoonkap Hahn
Life of this patent
Estimating the term…
Abstract
A brain drug delivery system having a catheter and a delivery assembly is provided. The catheter has a first channel with a first exit hole and a second channel with a second exit hole, both the first exit hole and the second exit hole being disposed at a distal end of the catheter, the second exit hole being adapted such that to cause a sideways turn of a movable inner plastic tube exiting therethrough. The catheter also being adapted to house a delivery assembly selectively within the first and second channel. While the delivery assembly has the movable inner plastic tube with a tube exit hole and an image-guided plunger being adapted to penetrate the movable inner plastic tube and push a powder form of drug microparticles via the tube exit hole.
Claims16
A brain drug delivery system comprising:
- a catheter having a first channel with a first exit hole and a second channel with a second exit hole, both the first exit hole and the second exit hole being disposed at a distal end of the catheter, the second exit hole being adapted such that to cause a sideways turn of a movable inner plastic tube exiting therethrough, wherein the sideways turn is of an obtuse angle;
- a delivery assembly that fits slidably and selectively into the first and second channel, and that is guidable by an imaging system, the delivery assembly having:
- the movable inner plastic tube having a tube exit hole and a sharp-edged tip;
- and
- an image-guided plunger being adapted to penetrate the movable inner plastic tube and push a powder form of drug microparticles via the tube exit hole.
A brain drug delivery system comprising:
- a catheter having a first channel with a first exit hole and a second channel with a second exit hole, both the first exit hole and the second exit hole being disposed at a distal end of the catheter, the second exit hole being adapted such that to cause a sideways turn of a movable inner plastic tube exiting therethrough, the catheter being adapted to house a delivery assembly selectively within the first and second channel;
- the delivery assembly having:
- the movable inner plastic tube having a tube exit hole;
- and
- an image-guided plunger being adapted to penetrate the movable inner plastic tube and push a powder form of drug microparticles via the tube exit hole.
A method of a brain drug delivery system comprising the steps of:
- selecting a catheter having a first channel with a first exit hole and a second channel with a second exit hole, both the first exit hole and the second exit hole being disposed at a distal end of the catheter, wherein the second exit hole being adapted such that to cause a sideways turn of a movable inner plastic tube exiting therethrough;
- selectively fitting a delivery assembly into the first or second channel of the catheter, the delivery assembly having the movable inner plastic tube having a tube exit hole and an image-guided plunger;
- inserting the catheter with the delivery assembly into a subject;
- positioning the distal end of the catheter in a proximity of a targeted wound area;
- pushing the delivery assembly into the wound area in the subject;
- retracting the image-guided plunger;
- loading drug particles into the movable inner plastic tube;
- reinserting the image-guided plunger into the movable inner plastic tube;
- and
- releasing the drug particles into the wound area either straight via the first exit hole or at an angle via the second exit hole.
Dependencies are inferred from the claim text.