Polyion complex capable of efficiently delivering mrna into living body, and drug and method for treating arthropathy in which said complex is used
AssigneeNanocarrier Co., Ltd.
InventorsKeiji ITAKA, Shinsuke OHBA, Yuichi TEI, Kazunori KATAOKA
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Abstract
The present invention provides a polyion complex which can efficiently deliver mRNA into a living body as well as a therapeutic agent and a therapeutic method of arthropathy in which the polyion complex is used. For example, there is provided a polyion complex comprising a cationic polymer and mRNA, wherein the cationic polymer is a polymer comprising a cationic unnatural amino acid as a monomer unit and the cationic unnatural amino acid is an amino acid having a group represented by —(NH—(CH2)2)p—NH2, wherein p is 2, 3 or 4, as a side chain.
Claims11
A polyion complex comprising a cationic polymer and mRNA,
- wherein the cationic polymer is a polymer comprising a cationic unnatural amino acid as a monomer unit and the cationic unnatural amino acid is an amino acid having a group represented by —(NH—(CH2)2)p—NH2, wherein p is 2, 3 or 4, as a side chain.
Dependencies are inferred from the claim text.