Nano-encapsulation using gras materials and applications thereof
AssigneeThe Trustees of Princeton University
InventorsNikolas T. WEISSMUELLER, Robert K. PRUD'HOMME
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Abstract
In one aspect, methods of preparing composite nanoparticle compositions are described herein. For example, in some embodiments, a method comprises providing a zein solution stream, an organic fluid stream including at least one additive and at least one buffer fluid stream. The zein solution stream, organic fluid stream and buffer fluid stream are delivered to a chamber for mixing at one or more rates sufficient to flash precipitate composite nanoparticles including the additive encapsulated by a shell comprising the zein.
Claims16
A composition comprising:
- a plurality of nanoparticles having a core-shell architecture, the core including an additive and the shell comprising zein, wherein surfactant is incorporated into the core-shell architecture, and the nanoparticles have an average size of 10 nm to 500 nm with a polydispersity index of less than 0.15.
A composition comprising:
- zein nanoparticles dispersed in an organic medium, the zein nanoparticles having a hydrophilic interior and hydrophobic exterior.
Dependencies are inferred from the claim text.