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US 2021/0259969 A1Published application
Compositions and methods involving transforming extracellular vesicles
OwnerMichael Sabbah, Atta Behfar +2inventors
InventorsMichael Sabbah, Atta Behfar, Christopher Livia, Timothy Peterson
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Abstract
An extracellular vesicle includes an exogenous therapeutic component. The exogenous therapeutic component can include a therapeutic polypeptide, a polynucleotide that encodes a therapeutic polypeptide, a therapeutic nucleic acid, or a therapeutic agent. In some embodiments, the extracellular vesicle includes an exosome or purified exosome product (PEP).
Claims13
An extracellular vesicle comprising an exogenous therapeutic component, the exogenous therapeutic component comprising:
- a therapeutic polypeptide;
- a polynucleotide that encodes a therapeutic polypeptide;
- a therapeutic nucleic acid;
- or
- a therapeutic agent.
2 more elements
A method of transforming an extracellular vesicle, the method comprising:
- obtaining extracellular vesicles;
- providing a therapeutic agent of interest;
- and
- introducing the therapeutic agent of interest into at least a portion of the extracellular vesicles.
1 more element
Dependencies are inferred from the claim text.