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US 2021/0259558 A1Published application
Haemodynamic data estimation
AssigneeBluedop Medical, Ltd.
InventorsDavid H. King, Mohammed Al-Qaisi
Life of this patent
Estimating the term…
Abstract
Techniques exist for measuring local blood velocity of flow rate waveforms in, for example, mammalian vascular segments. A method and system for deriving information on disease in vascular segments, for example mean pressure, drop in mean pressure and/or hydraulic resistance, from such measured waveforms is described. The waveforms can, for example, be measured non-invasively using Doppler ultrasound or magnetic resonance techniques. Form factors (Vff, Pff) for the velocity waveform and the central arterial pressure as determined. Stenosis may be detected by detecting changes, e.g, in Vff/Pff.
Claims32
1-26. (canceled)
A system, including:
- a non-invasive blood flow measurement device;
- a display device;
- and
- a processing device, in communication with the non-invasive blood flow measurement device and with the display device, configured to:
- receive blood flow data, generated by the blood flow measurement device, wherein the blood flow data includes a waveform of blood flow at a location in a segment of a vascular system of a mammal;
- receive a central mean pressure of the mammal;
- determine a first measure of a shape of the blood flow data and store the first measure in a storage device in association with the corresponding location, wherein the first measure represents a ratio between (1) a difference between a maximum magnitude of the blood flow data and a minimum magnitude of the blood flow data and (2) an average magnitude of the blood flow data;
- generate a local pressure estimate by division of the central mean pressure by a sum of (1) unity and (2) a ratio of a second measure to the first measure, wherein the second measure represents a ratio between (1) a difference between a maximum magnitude of a central pressure waveform and a minimum magnitude of the central pressure waveform and (2) the central mean pressure;
- and
- cause the display device to display a visual representation of the local pressure estimate.
7 more elements
One or more non-transitory computer readable media having instructions thereon that, in response to execution by one or more processing devices of an apparatus, cause the apparatus to:
- receive blood flow data, generated by a blood flow measurement device, wherein the blood flow data is a waveform of blood flow at a location in a segment of a vascular system;
- determine a first measure of a shape of the blood flow data and store the first measure in a storage device in association with the corresponding location, wherein the first measure represents a ratio between (1) a difference between a maximum magnitude of the blood flow data and a minimum magnitude of the blood flow data and (2) an average magnitude of the blood flow data;
- receive a central mean pressure of the vascular system;
- generate a local pressure estimate by division of the central mean pressure by a sum of (1) unity and (2) a ratio of a second measure to the first measure, wherein the second measure represents a ratio between (1) a difference between a maximum magnitude of a central pressure waveform and a minimum magnitude of the central pressure waveform and (2) the central mean pressure;
- and
- cause a display device to display a visual representation of the local pressure estimate.
3 more elements
A method of performing monitoring of a patient, comprising:
- receiving, by a processing apparatus, blood flow data, generated by a blood flow measurement device, wherein the blood flow data is a waveform of blood flow at a location in a segment of a vascular system;
- determining, by the processing apparatus, a first measure of a shape of the blood flow data and store the first measure in a storage device in association with the corresponding location, wherein the first measure represents a ratio between (1) a difference between a maximum magnitude of the blood flow data and a minimum magnitude of the blood flow data and (2) an average magnitude of the blood flow data;
- receiving, by the processing apparatus, a central mean pressure of the vascular system of the patient;
- generating, by the processing apparatus, a local pressure estimate by division of the central mean pressure by a sum of (1) unity and (2) a ratio of a second measure to the first measure, wherein the second measure represents a ratio between (1) a difference between a maximum magnitude of a central pressure waveform and a minimum magnitude of the central pressure waveform and (2) the central mean pressure;
- and
- causing, by the processing apparatus, a display device to display a visual representation of the local pressure estimate.
3 more elements
A patient monitoring system, including:
- a non-invasive blood flow measurement device;
- a display device;
- and
- a processing device, in communication with the non-invasive blood flow measurement device and with the display device, configured to:
- receive blood flow data, generated by the blood flow measurement device, wherein the blood flow data includes a waveform of blood flow at a location in a segment of a vascular system of a patient;
- determine a first measure of a shape of the blood flow data, wherein the first measure represents a ratio between (1) a difference between a maximum magnitude of the blood flow data and a minimum magnitude of the blood flow data and (2) an average magnitude of the blood flow data;
- generate a local pressure estimate by division of a central mean pressure by a sum of (1) unity and (2) a ratio of a second measure to the first measure, wherein the second measure represents a ratio between (1) a difference between a maximum magnitude of a central pressure waveform and a minimum magnitude of the central pressure waveform and (2) the central mean pressure;
- and
- cause the display device to display the local pressure estimate.
6 more elements
Dependencies are inferred from the claim text.