Probiotic compositions and methods
AssigneeH.J. Heinz Company Brands LLC
InventorsAndrea Budelli, Francesca Romana Fasano, Miryam Terzano, Lorenzo Bramati
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Abstract
The present invention features compositions and methods for modulation of the mucosal immune system. The compositions include foods fermented by the probiotic organism, Lactobacillus paracasei CBA L74 (International Depository Accession Number LMG P-24778). Alternatively the compositions can include L. paracasei CBA L74 and a physiologically acceptable carrier. In some embodiments, the L. paracasei CBA L74 can be non-replicating. The compositions can be administered to a subject having or at risk for gastrointestinal disorders related to immaturity of the immune system, infection or disease.
Claims14
1-50. (canceled)
A method of treating a subject having a gastrointestinal disorder, the method comprising:
- a) identifying a subject having a gastrointestinal disorder;
- b) administering to the subject an effective amount of a pharmaceutical composition comprising probiotic bacterium, Lactobacillus paracasei CBA L74, International Depository Accession Number LMG P-24778, wherein the Lactobacillus paracasei CBA L74 cells present in the composition are dead or have been rendered incapable of cell division.
(canceled)
56-68. (canceled)
A method of treating a subject having a gastrointestinal disorder, the method comprising:
- administering to the subject an effective amount of a pharmaceutical composition comprising a culture supernatant of probiotic bacterium, Lactobacillus paracasei CBA L74, International Depository Accession Number LMG P-24778, wherein any Lactobacillus paracasei CBA L74 cells present in the composition are dead or have been rendered incapable of cell division
Dependencies are inferred from the claim text.