Novel therapy
AssigneeSelectImmune Pharma AB
InventorsCatharina SVANBORG, Ines AMBITE
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Abstract
A method for treating cystitis, in particular acute cystitis, comprising administering to a patient in need thereof, an effective amount of a reagent selected from the group consisting of IL-1β inhibitors and MMP inhibitors, or proteins selected from ASC or NLRP-3. Diagnostic methods are also described and claimed.
Claims10
A method for treating cystitis comprising administering to a patient in need thereof, an effective amount of a reagent selected from the group consisting of IL-Iβ inhibitors and MMP inhibitors.
A method for diagnosing cystitis and in particular, acute cystitis, said method comprising detecting elevated levels of IL-Iβ or MMP-7 in urine of a subject.
A method for diagnosing susceptibility to cystitis, said method comprising detecting a mutation in a gene encoding a protein selected from ASC or NLRP-3 which results in downregulation of said gene and/or in the expression of inactive protein.
Dependencies are inferred from the claim text.