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US 2021/0246191 A1Published application
Compositions and Methods for Diagnosis and Treatment of Cancer
AssigneeBioNTech SE
InventorsUgur Sahin, Bonny Gaby Lui, Nadja Salomon, Joycelyn Wüstehube-Lausch, Matin Daneschdar, Hans-Ulrich Schmoldt, Markus Fiedler
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Abstract
The present invention relates to the diagnosis and treatment of diseases expressing Fibronectin Extra Domain B (EDB) such as diseases characterized by tissue remodeling and/or angiogenesis, in particular cancerous diseases, such as head and neck, brain, colorectal, lung, prostate and breast cancer. More particularly, the invention concerns peptides targeting Fibronectin Extra Domain B.
Claims51
A Fibronectin Extra Domain B (EDB) binding peptide which comprises the amino acid sequence motif Arg-Ile/Val-Arg.
Dependencies are inferred from the claim text.