# US 2021/0241892 A1 · Providing enhanced patient updates to facilitate precision therapy

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- Number: US 2021/0241892 A1
- Document ID: US20210241892A1
- Status: Published application
- Kind: A1
- Application number: 17/179,870
- Filed: 2021-02-19
- Published: 2021-08-05
- Earliest claimed: 2018-06-15
- Assignees: Xact Laboratories, LLC
- Applicants: Xact Laboratories, LLC
- Inventors: Rob Todd; Jerry Wrobel; John Pigott
- Web page: https://patentgrep.com/patent/US20210241892A1

## CPC

- G16H 40/20: for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
- G06F 16/2457: with adaptation to user needs
- G06Q 10/10: Office automation; Time management
- G06Q 40/08: Insurance
- G16B 20/00: ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B 50/00: ICT programming tools or database systems specially adapted for bioinformatics
- G16H 10/40: for data related to laboratory analysis, e.g. patient specimen analysis
- G16H 10/60: for patient-specific data, e.g. for electronic patient records
- G16H 20/10: relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H 40/67: for remote operation
- G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems
- G16H 50/70: for mining of medical data, e.g. analysing previous cases of other patients
- G16H 70/20: relating to practices or guidelines
- G16H 70/40: relating to drugs, e.g. their side effects or intended usage
- G16H 70/60: relating to pathologies
- G06Q 30/04: Billing or invoicing
- G16H 15/00: ICT specially adapted for medical reports, e.g. generation or transmission thereof
- H04M 3/5158: {in combination with automated outdialling systems (devices for signalling identity of wanted subscriber H04M1/26)}
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N)
- G06Q: INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G16B: BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- H04M: TELEPHONIC COMMUNICATION (circuits for controlling other apparatus via a telephone cable and not involving telephone switching apparatus G08)

## Abstract

System and methods for providing enhanced patient updates to facilitate precision therapy are provided. Medical information is received from a transmitting one of a number of electronic health records (“EHR”) systems at a laboratory information system (“LIS”). Where the received medical information comprises prescribed medications designated as ineffective or undereffective for the particular patient based on a retrieved genetic testing results for the patient, the EHR systems are instructed to designate the prescribed medications as an allergy. Where the received medical information comprises new diagnosis information eligible for genetic testing based on retrieved eligibility rules for the particular patient, a suggested order is transmitted to the transmitting EHR system.

## Claims

### Claim 1

A system for providing enhanced patient updates to facilitate precision therapy,
said system comprising:
a number of electronic health record (“EHR”) systems, each associated with a healthcare provider, and each comprising patient data for at least a particular patient;
a laboratory information system (“LIS”) in electronic communication with each of the number of EHR systems, wherein said LIS comprises a testing database with genetic testing information for at least the particular patient, an eligibility database with insurance eligibility rules applicable to at least the particular patient, and software instructions stored at one or more electronic storage devices, which when executed, configures one or more processors to:
receive medical information from a transmitting one of the number of EHR systems at the LIS;
if the received medical information comprises new treatment information:
query the testing database for genetic testing results associated with the particular patient; and
determine if the new treatment information comprises one or more prescribed medications designated as ineffective or undereffective for the particular patient based on the retrieved genetic testing results for the particular patient, and if so, instructing each of the number of EHR systems to designate the one or more prescribed medications designated as ineffective or undereffective as an allergy at each of the number of EHR systems;
if the received medical information comprises new diagnosis information:
query the eligibility database to retrieve eligibility rules for the particular patient; and
determine if genetic testing is eligible under the retrieved eligibility rules, and if so, transmit a suggested order for the eligible genetic testing to the transmitting one of the number of EHR systems.

### Claim 2 (depends on 1)

The system of claim 1 further comprising:
additional software instructions stored at the one or more electronic storage devices, which when executed, configures the one or more processors to transmit the received medical information to each of the number of EHR systems other than the transmitting one of the number of EHR systems.

### Claim 3 (depends on 2)

The system of claim 2 further comprising:
a pharmacy benefits manager (“PBM”) system associated with the particular patient and in electronic communication with the LIS.

### Claim 4 (depends on 3)

The system of claim 3 further comprising:
additional software instructions stored at the one or more electronic storage devices, which when executed, configures the one or more processors to transmit the received medical information to the PBM system.

### Claim 5 (depends on 4)

The system of claim 4 further comprising:
a pharmacy system associated with the PBM system and the particular patent;
a patient file database associated with the PBM system; and
software instructions associated with the PBM system and stored on one or more electronic storage devices associated with the PBM system, which when executed, configure one or more processors associated with the PBM system to:
query the patient file database for allergy information associated with the particular patient;
determine if the new treatment information comprises one or more ordered prescription medication flagged as an allergy in the retrieved data associated with the particular patient; and
generate and transmit an electronic notification to the pharmacy system requesting that prescriptions for the one or more ordered prescription medications flagged as an allergy not be filled.

### Claim 6 (depends on 2)

The system of claim 2 further comprising:
a payor system associated with the particular patent and in electronic communication with the LIS.

### Claim 7 (depends on 6)

The system of claim 6 further comprising:
additional software instructions stored at the one or more electronic storage devices, which when executed, configures the one or more processors to transmit the received medical information to the payor system.

### Claim 8 (depends on 7)

The system of claim 7 wherein:
a patient file database associated with the payor system; and
software instructions associated with the payor system and stored on one or more electronic storage devices associated with the payor system, which when executed, configure one or more processors associated with the payor system to:
query the patient file database for allergy information associated with the particular patient;
determine if the new treatment information comprises one or more ordered prescription medications flagged as an allergy in the retrieved data associated with the particular patient; and
generate and transmit a claim denial for the one or more ordered prescription medications flagged as an allergy in the retrieved data.

### Claim 9 (depends on 2)

The system of claim 2 wherein:
at least a first one of the number of EHR systems is associated with a hospice provider;
at least a second one of the number of EHR systems is associated with a hospital; and
at least a third one of the number of EHR systems is associated with a primary care provider.

### Claim 10 (depends on 2)

The system of claim 2 further comprising:
at least one healthcare information exchange electronically interposed between at least some of the number of EHR systems at the LIS.

### Claim 11 (depends on 2)

The system of claim 2 further comprising:
additional software instructions stored at the one or more electronic storage devices, which when executed, configures the one or more processors to convert the received medical information from a format specific to the transmitting one of the number of EHR systems into formats specific to each of the number of EHR systems.

### Claim 12 (depends on 3)

The system of claim 3 further comprising:
an alternative medication database comprising a list of alternative treatment options, each of which is associated with one or more medications; and
additional software instructions stored at the one or more electronic storage devices, which when executed, configures the one or more processors:
query the alternative medication database to retrieve alternative treatment options associated with the one or more prescribed medications designated as ineffective or undereffective for the particular patient; and
transmit the alternative treatment options to the transmitting one of the number of EHR systems.

### Claim 13 (depends on 12)

The system of claim 12 further comprising:
additional software instructions stored at the one or more electronic storage devices, which when executed, configure the one or more processors to: transmit the alternative treatment options to the PBM system.

### Claim 14 (depends on 1)

The system of claim 1 further comprising:
a call center in electronic communication with said LIS and configured to receive the suggested order for the eligible genetic testing and automatically initiate a contact campaign informing said particular patient of said subset of eligibility for testing.

### Claim 15 (depends on 1)

The system of claim 1 further comprising:
a patient file database at the LIS;
additional software instructions stored at the one or more electronic storage devices, which when executed, configures the one or more processors to:
store received medical information at the patient file database;
receive a request from a new EHR system for access to data for the particular patient stored at the patient file;
query the patient file database to retrieve the data for the particular patient; and
transmit the retrieved data to the new EHR system.

### Claim 16 (depends on 1)

The system of claim 1 further comprising:
a patient file database at the LIS;
additional software instructions stored at the one or more electronic storage devices, which when executed, configure the one or more processors to:
store received medical information at the patient file database;
receive a request from one of the number of EHR system to transmit data for the particular patient stored at the patient file to a new EHR system;
query the patient file database to retrieve the data for the particular patient; and
transmit the retrieved data to the new EHR system.

### Claim 17

A system for providing enhanced patient updates to facilitate precision therapy,
said system comprising:
a number of electronic health record (“EHR”) systems, each associated with a healthcare provider, each of which comprise patient data for at least a particular patient;
a laboratory information system (“LIS”) in electronic communication with each of the number of EHR systems, wherein said LIS comprises a testing database with genetic testing information, an eligibility database with insurance eligibility rules, a patient file database comprising medical information for the particular patient, and software instructions stored at one or more electronic storage devices, which when executed, configures one or more processors to:
receive medical information from a transmitting one of the number of EHR systems at the LIS;
update the medical information for the particular patient with the received medical information at the patient file database;
if the received medical information comprises new treatment information:
query the testing database for genetic testing results associated with the particular patient; and
determine if the new treatment information comprises one or more prescribed medications designated as ineffective or undereffective for the particular patient based on the retrieved genetic testing results for the particular patient, and if so, instructing to each of the number of EHR systems to designate the one or more prescribed medications designated as ineffective or undereffective as an allergy at each of the number of EHR systems;
if the received medical information comprises new diagnosis information:
query the eligibility database to retrieve eligibility rules for the particular patient; and
determine if genetic testing is eligible under the retrieved eligibility rules, and if so, transmit a suggested order for the eligible genetic testing to the transmitting one of the number of EHR systems; and
transmit the received medical information to each of the number of EHR systems other than the transmitting one of the number of EHR systems.

### Claim 18 (depends on 17)

The system of claim 17 further comprising:
additional software instructions stored at the one or more electronic storage devices, which when executed, configure the one or more processors to:
store received medical information at the patient file database, wherein said medical information is stored in a common format;
receive a request from one or the number of EHR system to transmit data for the particular patient stored at the patient file to a new EHR system;
query the patient file database to retrieve the data for the particular patient;
covert the patient file into a format specific to the new EHR system; and
transmit the retrieved data to the new EHR system.

### Claim 19 (depends on 17)

The system of claim 17 further comprising:
a pharmacy benefits manager (“PBM”) system associated with the particular patient, a pharmacy system associated with the particular patient, and in electronic communication with the LIS;
a payor system associated with the particular patent and in electronic communication with the LIS; and
additional software instructions stored at the one or more electronic storage devices, which when executed, configures the one or more processors to transmit the received medical information to the PBM system and the payor system, wherein a first one of the number of EHR systems is associated with a hospice provider, a second one of the number of EHR systems is associated with a VA healthcare provider, a third one of the number of EHR systems is associated with a hospital, a fourth one of the number of EHR systems is associated with a specialist, a fifth one of the number of EHR systems is associated with a primary care provider.

### Claim 20

A method for providing enhanced patient updates to facilitate precision therapy,
said method comprising the steps of:
receiving medical information for a particular patient from a transmitting one of a number of electronic health record (“EHR”) systems at a laboratory information system (“LIS”);
updating the medical information for the particular patient with the received medical information at a patient file database;
determining that the received medical information comprises new treatment information;
querying a testing database for genetic testing results associated with the particular patient;
determining that the new treatment information comprises one or more prescribed medications designated as ineffective or undereffective for the particular patient based on the retrieved genetic testing results for the particular patient;
instructing each of a number of EHR systems to designate the one or more prescribed medications designated as ineffective or undereffective as an allergy at each of the number of EHR systems;
determining that said medical information for the particular patient comprises new diagnosis information;
querying an eligibility database to retrieve eligibility rules for the particular patient;
determining that genetic testing is eligible under the retrieved eligibility rules;
transmitting a suggested order for the eligible genetic testing to the transmitting one of the number of EHR systems; and
transmitting the received medical information to each of the number of EHR systems other than the transmitting one of the number of EHR systems.