# US 2021/0241481 A1 · Method for determining annulus size of bicuspid valve

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- Number: US 2021/0241481 A1
- Document ID: US20210241481A1
- Status: Published application
- Kind: A1
- Application number: 17/052,321
- Filed: 2019-04-22
- Published: 2021-08-05
- Earliest claimed: 2018-05-03
- Assignees: The Asan Foundation; University of Ulsan Foundation for Industry Cooperation
- Applicants: The Asan Foundation; University of Ulsan Foundation for Industry Cooperation
- Inventors: Dong Hyun YANG; June Goo LEE; Hyun Jung KOO; Jung-Min AHN
- Web page: https://patentgrep.com/patent/US20210241481A1

## CPC

- G06T 7/60: Analysis of geometric attributes
- G06T 7/62: of area, perimeter, diameter or volume
- A61B 5/1075: {for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer (A61B8/0858 takes precedence)}
- A61B 6/5217: {extracting a diagnostic or physiological parameter from medical diagnostic data}
- A61B 6/5223: {generating planar views from image data, e.g. extracting a coronal view from a 3D image}
- A61B 8/5223: {for extracting a diagnostic or physiological parameter from medical diagnostic data (for algorithms to analyse biomedical images G06T7/0012)}
- A61B 8/523: {for generating planar views from image data in a user selectable plane not corresponding to the acquisition plane}
- G06T 7/0012: {Biomedical image inspection}
- A61B 5/0044: {for the heart}
- A61B 6/032: {Transmission computed tomography [CT]}
- A61B 6/503: {for diagnosis of the heart}
- A61B 8/0883: {for diagnosis of the heart}
- A61B 8/483: {involving the acquisition of a 3D volume of data}
- G06T 2207/10072: Tomographic images
- G06T 2207/10081: Computed x-ray tomography [CT]
- G06T 2207/10088: Magnetic resonance imaging [MRI]
- G06T 2207/10132: Ultrasound image
- G06T 2207/10136: 3D ultrasound image
- G06T 2207/30048: Heart; Cardiac
- G06T 2207/30101: Blood vessel; Artery; Vein; Vascular
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A method for determining the size of a bicuspid annulus of bicuspid, including acquiring an image of the heart including the left ventricle and the aorta; generating a first plane, which includes a line that passes through two base points in the bicuspid of the image of the heart; and generating multiple second planes, which are obtained per each rotation, while rotating the first plane multiple times by a predetermined angle about the line that passes through the two base points; measuring the cross-sectional area of each of at least one of the left ventricle and the aorta, which are formed on the first plane and the multiple second planes; selecting a plane for measuring the size of a bicuspid annulus among the first plane and the multiple second planes based on the measured cross-sectional area; and measuring the size of the bicuspid annulus based on the selected plane.

## Claims

### Claim at position 1

1-11. (canceled)

### Claim 12

A system for determining a size of a bicuspid annulus of bicuspid, the system comprising:
an image acquisition unit which acquires an image of a heart comprising a left ventricle and an aorta;
a plane generation unit which generates a first plane comprising a line that passes through two base points in the bicuspid of the image of the heart and generates multiple second planes by rotating the first plane multiple times by a predetermined angle about the line that passes through the two base points;
a cross-sectional area measurement unit which measures the cross-sectional area of each of at least one of the left ventricle and the aorta, which are formed on the first plane and the multiple second planes;
a plane selection unit which selects a plane for measuring the size of the bicuspid annulus among the first plane and the multiple second planes based on the measured cross-sectional area; and
a bicuspid annulus size measurement unit which measures the size of the bicuspid annulus based on the selected plane.

### Claim 13

A system for determining a size of a bicuspid annulus of bicuspid, the system comprising:
an image acquisition unit which acquires an image of a heart comprising a left ventricle and an aorta;
a plane generation unit which generates a first plane that passes through a sinus of Valsalva of the bicuspid, with respect to the bicuspid that passes through three base points comprising a raphe of the image of the heart, and generates multiple second planes by moving the first plane in parallel by a predetermined interval in the direction of the left ventricle outflow; and
a bicuspid annulus size measurement unit which, in a case where the three base points disappear from the multiple second planes, measures the size of the bicuspid annulus based on the plane generated immediately before the last parallel movement among the multiple second planes.

### Claim 14 (depends on 12)

The system of claim 12, wherein the angle rotated multiple times by the predetermined angle is 360°.

### Claim 15 (depends on 12)

The system of claim 12, wherein the bicuspid is a bicuspid without a raphe.

### Claim 16 (depends on 12)

The system of claim 12, wherein the plane for measuring the size of the bicuspid annulus is a plane having the smallest cross-sectional area among the measured cross-sectional areas.

### Claim 17 (depends on 16)

The system of claim 16, wherein the bicuspid annulus size measurement unit measures the smallest cross-sectional area and determines the size of the bicuspid annulus based on the size of the smallest cross-sectional area.

### Claim 18 (depends on 12)

The system of claim 12, wherein the image of the heart is at least one among a computed tomography (CT) image, a magnetic resonance imaging (MRI) image, and an echocardiography image.

### Claim 19

A computer-readable recording medium on which a program comprising instructions for causing a processor to perform a method for determining a size of a bicuspid annulus of bicuspid, the method comprising:
acquiring an image of the heart comprising a left ventricle and an aorta;
generating a first plane, which comprises a line that passes through two base points in the bicuspid of the image of the heart and generating multiple second planes, which are obtained per each rotation, while rotating the first plane multiple times by a predetermined angle about the line that passes through the two base points;
measuring a cross-sectional area of each of at least one of the left ventricle and the aorta, which are formed on the first plane and the multiple second planes;
selecting a plane for measuring the size of a bicuspid annulus among the first plane and the multiple second planes based on the measured cross-sectional area; and
measuring the size of the bicuspid annulus based on the selected plane.
