# US 2021/0241456 A1 · Utilizing personal communications devices for medical testing

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- Number: US 2021/0241456 A1
- Document ID: US20210241456A1
- Status: Published application
- Kind: A1
- Application number: 17/238,434
- Filed: 2021-04-23
- Published: 2021-08-05
- Earliest claimed: 2014-05-12
- Assignees: Healthy.Io Ltd.
- Applicants: Healthy.Io Ltd.
- Inventors: Yonatan ADIRI; ldo OMER; Shachar MENDELOWITZ; Roee SALOMON
- Web page: https://patentgrep.com/patent/US20210241456A1

## CPC

- G06T 7/90: Determination of colour characteristics
- G01N 21/78: producing a change of colour
- G01N 21/8483: {Investigating reagent band (test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04)}
- G06T 5/90: Dynamic range modification of images or parts thereof
- G06T 5/94: based on local image properties, e.g. for local contrast enhancement
- G06T 7/0012: {Biomedical image inspection}
- G06V 10/56: relating to colour
- G01N 2201/0221: Portable; cableless; compact; hand-held
- G06T 2207/10024: Color image
- G06T 2207/30072: Microarray; Biochip, DNA array; Well plate
- G06V 2201/03: Recognition of patterns in medical or anatomical images
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- G06V: IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING

## Abstract

Systems and methods for analyzing visible chemical reactions are provided. In one implementation, the method may include receiving from an image sensor associated with a mobile communications device an image of a reagent pad in proximity to a colorized surface having at least one pair of colored reference elements. The method includes identifying in the image the reagent pad, a first colored reference element, and a second colored reference element. Thereafter, the method includes using the first colored reference element and the second colored reference element to determine an extent of a chemical reaction on the reagent pad irrespective of local illumination conditions. Then the method includes causing the mobile communications device to provide data based on the extent of the chemical reaction.

## Claims

### Claim at position 1

1-20. (canceled)

### Claim 21

A non-transitory computer readable medium containing instructions that, when executed by at least one processor, cause the at least one processor to carry out a method for analyzing visible chemical reactions, the method comprising:
receiving from an image sensor associated with a mobile communications device an image of a reagent pad in proximity to a colorized surface having a plurality of colored reference elements designed to be used together to determine an extent of a reaction on the reagent pad;
identifying in the image the reagent pad;
identifying in the image a first colored reference element having a first color;
identifying in the image a second colored reference element having a second color differs from the first color; using the first colored reference element and the second colored reference element to determine an extent of a chemical reaction on the reagent pad irrespective of local illumination conditions; and
providing data based on the extent of the chemical reaction.

### Claim 22 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein the method further includes:
identifying illumination parameters indicative of the local illumination conditions, based on the plurality of colored reference elements; and
determining the extent of the chemical reaction on the reagent pad irrespective of local illumination conditions based on the identified illumination parameters.

### Claim 23 (depends on 21)

The non-transitory computer readable medium product of claim 21, wherein the method further includes:
calculating a normalized reagent test color based on the first colored reference element and the second colored reference element; and
determining the extent of the chemical reaction on the reagent pad irrespective of local illumination conditions based on the normalized reagent test color.

### Claim 24 (depends on 23)

The non-transitory computer readable medium product of claim 23, wherein the image includes a depiction of a plurality of reagent pads and the method further includes:
using the normalized reagent test color to determine a uniform color for pixels associated with each of the plurality of reagent pads; and
determining the extent of the chemical reaction on each of the plurality of reagent pads based on the uniform color associated with each of the plurality of reagent pads.

### Claim 25 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein the reagent pad is located on a dipstick.

### Claim 26 (depends on 5)

The non-transitory computer readable medium of claim 5, wherein the dipstick includes a plurality of reagent pads, and the colorized surface depicted in the image includes a plurality of pairs of colored reference elements.

### Claim 27 (depends on 26)

The non-transitory computer readable medium of claim 26, wherein the method further comprises calculating a first normalized color for a first reagent pad using at least one of the plurality of pairs of colored reference elements, and calculating a second normalized color for a second reagent pad using at least one other of the plurality of pairs of colored reference elements.

### Claim 28 (depends on 26)

The non-transitory computer readable medium of claim 26, wherein the colorized surface depicted in the image includes at least ten pairs of colored reference elements.

### Claim 29 (depends on 26)

The non-transitory computer readable medium of claim 26, wherein the method further comprises analyzing relations among a plurality of colored test reagents using a coordinate system.

### Claim 30 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein the reagent pad is configured for use in urinalysis.

### Claim 31 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein the provided data based on the extent of the chemical reaction is medical data associated with a plurality of differing urinary properties.

### Claim 32 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein providing the data based on the extent of the chemical reaction includes causing the mobile communications device to provide the data.

### Claim 33 (depends on 32)

The non-transitory computer readable medium of claim 32, wherein causing the mobile communications device to provide the data includes causing the mobile communications device to transmit the data to a medical entity associated with a user of the mobile communications device.

### Claim 34 (depends on 32)

The non-transitory computer readable medium of claim 32, wherein causing the mobile communications device to provide the data includes causing the mobile communications device to display the data on a screen associated with the mobile communications device.

### Claim 35 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein the at least one processor includes a processor within the mobile communications device.

### Claim 36 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein the at least one processor includes a server remote from the mobile communications device.

### Claim 37 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein the first and the second colored reference elements of a pair of colored reference elements of the plurality of colored reference elements share substantially a same color.

### Claim 38 (depends on 21)

The non-transitory computer readable medium of claim 21, wherein the method further comprises:
identifying in the image, at least one position marker distinguished from the plurality of colored reference elements;
analyzing the image using the at least one position marker to determine that an orientation of the reagent pad is an undesired orientation; and
in response to the determination that the orientation of the reagent pad is an undesired orientation, providing a notification to a user.

### Claim 39 (depends on 18)

The non-transitory computer readable medium of claim 18, wherein the at least one position marker has a color that differs from the first and second colors.

### Claim 40

A method for analyzing visible chemical reactions, the method comprising:
receiving from an image sensor associated with a mobile communications device an image of a reagent pad in proximity to a colorized surface having a plurality of colored reference elements designed to be used together to determine an extent of a reaction on the reagent pad;
identifying in the image the reagent pad;
identifying in the image a first colored reference element having a first color;
identifying in the image a colored reference element having a second color differs from the first color; and
using the first colored reference element and the second colored reference element to determine an extent of a chemical reaction on the reagent pad irrespective of local illumination conditions; and
providing data based on the extent of the chemical reaction.
