# US 2021/0239451 A1 · Forward looking rgb/optical coherence tomography duplex imager

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- Number: US 2021/0239451 A1
- Document ID: US20210239451A1
- Status: Published application
- Kind: A1
- Application number: 17/236,901
- Filed: 2021-04-21
- Published: 2021-08-05
- Earliest claimed: 2020-01-30
- Assignees: Veravanti Inc.
- Applicants: VerAvanti Inc.
- Inventors: Gerald McMorrow; Jongtae Yuk
- Web page: https://patentgrep.com/patent/US20210239451A1

## CPC

- G01B 9/02091: Tomographic interferometers, e.g. based on optical coherence
- A61B 1/0005: {combining images e.g. side-by-side, superimposed or tiled}
- A61B 1/0017: {Details of single optical fibres, e.g. material or cladding}
- A61B 1/00172: {with means for scanning}
- A61B 3/102: {for optical coherence tomography [OCT]}
- A61B 5/0066: {Optical coherence imaging}
- A61B 5/0084: {for introduction into the body, e.g. by catheters (A61B5/1459 takes precedence)}
- G01B 9/0203: {With imaging systems}
- G01B 9/02087: {Combining two or more images of the same region}
- A61B 2090/3735: {Optical coherence tomography [OCT]}
- G01B 2290/65: Spatial scanning object beam
- G01B: MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

Systems, methods, and devices for directed to duplex imaging techniques for combining high-resolution surface images obtained with a Scanning Fiber Endoscope (SFE), and high-resolution penetrating OCT images obtained through Optical Coherence Tomography (OCT), from a SFE, and interleaving frames to improve resolution and identify below surface information of biological structures.

## Claims

### Claim 1

A method for acquiring OCT B-mode images, comprising:
oscillating a cantilever scanning fiber within a probe along a scanning path, wherein the probe is configured to obtain reflected light generated by the scanning fiber, and the oscillating scanning path increases in amplitude over time;
obtaining a plurality of A-line scans from the obtained reflected light, each A-line scan obtained at a point along the oscillating scanning path that the scanning fiber reaches a minimum speed; and
constructing a B-mode image from the plurality of A-line scans.

### Claim 2 (depends on 1)

The method of claim 1, wherein the oscillating scanning path is defined by two sinusoidal inputs.

### Claim 3 (depends on 1)

The method of claim 1, further comprising constructing a plurality of B-mode images from the plurality of A-line scans, each B-mode image offset by a scanning angle.

### Claim 4 (depends on 3)

The method of claim 3, further comprising interleaving the plurality of B-mode images to construct a three-dimensional image.

### Claim 5 (depends on 1)

The method of claim 1, further comprising:
constructing a plurality of RGB images from the reflected light obtained while the scanning fiber moves along the oscillating scanning path.

### Claim 6 (depends on 5)

The method of claim 5, further comprising
interleaving the plurality of RGB images to create a first image of a duplex image; and
interleaving the plurality B-mode images to create a second image of the duplex image.

### Claim 7 (depends on 1)

The method of claim 1, wherein the probe is in a scanning fiber endoscope.

### Claim 8 (depends on 1)

The method of claim 1, further comprising:
analyzing the reflected light generated by the scanning fiber with an interferometer to identify an origin and a location of the reflected light.

### Claim 9 (depends on 8)

The method of claim 8, further comprising:
utilizing a reference arm to provide a reference point for the interferometer.

### Claim 10

A non-transitory computer readable storage medium comprising instructions stored thereon that cause a computing system to at least:
oscillate a cantilever scanning fiber within a probe along a scanning path, wherein the probe is configured to obtain reflected light generated by the scanning fiber, the oscillating scanning path increasing in amplitude over time;
obtain a plurality of A-line scans from the obtained reflected light, each A-line scan obtained at a point along the oscillating scanning path where a speed of the scanning fiber is at a minimum; and
construct a B-mode image from the plurality of A-line scans.

### Claim 11 (depends on 10)

The non-transitory computer readable storage medium of claim 10, further comprising instructions to cause the computing system to at least construct a plurality of B-mode images from the plurality of A-line scans, each B-mode image offset by a scanning angle.

### Claim 12 (depends on 11)

The non-transitory computer readable storage medium of claim 11, further comprising instructions to cause the computing system to at least interleave the plurality of B-mode images to construct a three-dimensional image.

### Claim 13 (depends on 11)

The non-transitory computer readable storage medium of claim 11, further comprising instructions to cause the computing system to at least:
construct a plurality of RGB images from the reflected light obtained while the scanning fiber moves along the oscillating scanning path; and
interleave the plurality B-mode images as a first image of a duplex image and interleave the plurality of RGB images as a second image of the duplex image.

### Claim 14 (depends on 10)

The non-transitory computer readable storage medium of claim 10, wherein the B-mode image depicts an area within a blood vessel lumen.

### Claim 15 (depends on 10)

The computer readable storage medium of claim 10, wherein the B-mode image identifies an occlusion within a blood vessel.

### Claim 16 (depends on 10)

The non-transitory computer readable storage medium of claim 10, further comprising instructions to cause the computing system to at least:
analyze the reflected light generated by the scanning fiber with an interferometer to identify an origin and a location of the reflected light.

### Claim 17 (depends on 16)

The non-transitory computer readable storage medium of claim 16, further comprising instructions to cause the computing system to at least:
utilize a reference arm to provide a reference point for the interferometer.
