Marker of fetal trophoblast cell, identification method, detection kit and use thereof
AssigneeSuzhou Junhui Biotechnology Co., Ltd.
InventorsQihui Shi, Chunying Wang
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Abstract
A marker of fetal trophoblast cells, an identification method, a detection kit and the use thereof. The identification method comprises performing dyeing treatment on a sample containing fetal trophoblast cells with a fluorescence-labeled HK2 antibody substance, and then performing fluorescence detection, wherein HK2 positive cells are target cells. The kit comprises a fluorescence-labeled HK2 antibody substance and a cell nucleus dye. The above-mentioned technical solution can sensitively and reliably detect fetal trophoblast cells in the cervical mucus or blood samples of pregnant women in the first trimester, and especially can be used for prenatal diagnosis in early pregnancy.
Claims14
(canceled)
A method for identifying fetal trophoblast cells, comprising incubating a sample containing fetal trophoblast cells with a labeled anti-HK2 (hexokinase 2) antibody, and identifying cells bound to the labeled anti-HK2 antibody as fetal trophoblast cells.
A kit for detecting fetal trophoblast cells, wherein the kit includes a fluorescently labeled HK2 antibody substance.
(canceled)
Dependencies are inferred from the claim text.