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US 2021/0230694 A1Published application
Nasal genes used to identify, characterize, and diagnose viral respiratory infections
AssigneeUniversity of Rochester
InventorsGregory Storch, Jinsheng Yu, Thomas J. Mariani
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Abstract
The present disclosure provides molecular methods to improve the rapid diagnosis of respiratory infections. In general, the present disclosure provides method of detecting host gene signatures which aid in determining the etiology of a respiratory infection and thereby improve the treatment.
Claims22
A method for detecting a respiratory infection in a subject, the method comprising:
- a) measuring the level of expression of one or more host gene in a biological sample obtained from a subject;
- and
- b) comparing the level of the at least one host gene with a predetermined reference level, wherein if the level of the at least one host gene is above or below the respective reference value, the subject is determined to have a respiratory infection.
A method of treating an acute respiratory illness (ARI) in a subject comprising:
- a) measuring the level of expression of one or more host gene in a biological sample obtained from a subject;
- b) comparing the level of the at least one host gene with a predetermined reference level, wherein if the level of the at least one host gene is above or below the respective reference value, the subject is determined to have a respiratory infection;
- and
- c) administering to said subject an appropriate treatment regimen based on the type of respiratory infection.
1 more element
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-28. (canceled)
Dependencies are inferred from the claim text.