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US 2021/0230634 A1Published application
Synp159, a promoter for the expression of genes
AssigneeFriedrich Miescher Institute for Biomedical Research
InventorsDominik HARTL, Josephine JUETTNER, Arnaud KREBS, Botond ROSKA, Dirk SCHUEBELER
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Abstract
The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.
Claims20
An expression cassette comprising:
- an isolated nucleic acid molecule comprising the nucleic acid sequence of SEQ ID NO:1;
- and
- a nucleic acid sequence encoding for a gene,
- wherein said isolated nucleic acid molecule is operatively linked to the nucleic acid sequence encoding for the gene, and said isolated nucleic acid molecule is effective to drive expression of the gene in a cell.
1 more element
Dependencies are inferred from the claim text.