Compositions and methods for delivery of aav
AssigneeVoyager Therapeutics, Inc.
InventorsDinah Wen-Yee Sah, Holger Patzke, Todd Carter, Jinzhao Hou, Giridhar Murlidharan
Life of this patent
Estimating the term…
Abstract
The disclosure provides compositions and methods for the preparation, manufacture, formulation and therapeutic use of adeno-associated virus (AAV) particles for the prevention and/or treatment of diseases.
Claims100
An adeno-associated viral (AAV) particle comprising a capsid and a viral genome, wherein said capsid penetrates the blood brain barrier following delivery of the AAV particle, wherein the capsid is VOY1101 or VOY801.
An AAV particle comprising a capsid and a viral genome, wherein said capsid penetrates the blood brain barrier following delivery of the AAV particle, wherein the nucleotide sequence of the capsid is at least 95% identical to SEQ ID NO:
- 1825.
An AAV particle comprising a capsid and a viral genome, wherein said capsid penetrates the blood brain barrier following delivery of the AAV particle, wherein the nucleotide sequence of the capsid is at least 95% identical to SEQ ID NO:
- 1824.
Dependencies are inferred from the claim text.