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US 2021/0230595 A1Published application
Biodegradable and clinically-compatible nanoparticles as drug delivery carriers
Assignee1Globe Health Institute LLC
InventorsChiang J. Li, Youzhi Li, Keyur Gada, Xiaoshu Dai
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Abstract
The present invention relates to the composition of a nanoparticle based on a magnesium salt, and methods of drug delivery using the nanoparticle. A preferred embodiment uses magnesium phosphate, with or without a shell to deliver aiRNA and/or siRNA. The nanoparticles of the present invention are also effective when administered orally.
Claims27
1-72. (canceled)
A nanoparticle comprising:
- a core comprising an inorganic magnesium salt, and a medically useful agent comprising a nucleic acid, wherein the core is encapsulated by a shell, and
- wherein the shell comprises a protein or peptide.
Dependencies are inferred from the claim text.