The core domain of annexins and uses thereof in antigen delivery and vaccination
AssigneeDeutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
InventorsFatmire BUJUPI, Peter KRAMMER, Heiko WEYD
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Abstract
The present disclosure provides immunogenic compositions, such as vaccines, including DNA vaccines, and uses thereof, e.g., which include an annexin core domain to mediate efficient antigen delivery and antigen presentation in order to induce an antigen-specific immune response and/or to treat or prevent infectious diseases and/or cancer.
Claims16
An isolated annexin core domain comprising an amino acid sequence of a core domain as comprised in a sequence selected from the group of SEQ ID Nos. 1 to 3 and 6 to 8, or an amino acid sequence that is at least 50% identical to an amino acid sequence of an annexin core domain as comprised in a sequence selected from the group of SEQ ID Nos. 1 to 3 and 6 to 8.
Dependencies are inferred from the claim text.