Method for separating natural substance mixtures by means of scpc
AssigneeSpectrum Therapeutics GMBH
InventorsMichael ENGLERT, Andreas RUTZ
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Abstract
The invention relates to a method for separating natural substance mixtures, in particular those consisting of plant extracts, and for isolating and purifying and obtaining same, by means of sequential centrifugal partition chromatography (sCPC).
Claims26
A method for separating and/or purifying natural substances from plant extracts, comprising at least one liquid-liquid partition chromatography step, wherein a continuous change of the stationary phase to the mobile phase and vice versa takes place, and wherein one or more fractions are removed.
(canceled)
(canceled)
ces from plant extracts according to claim 11, wherein that the solvents at least contain:
- a.) n-heptane and/or acetonitrile, n-heptane/acetonitrile;
- b.) n-heptane/ethyl acetate/acetonitrile;
- c.) n-heptane/ethyl acetate/t-butyl methyl ether/acetonitrile;
- d.) n-heptane/ethyl acetate/methanol/water;
- e.) n-heptane/ethanol/water.
The method for separating and/or purifying natural
A method for separating and/or purifying natural substances from plant extracts, comprising at least one liquid-liquid partition chromatography step, wherein a continuous change of the stationary phase to the mobile phase and vice versa takes place, wherein at least one pure substance is removed.
Dependencies are inferred from the claim text.