Addition salt of s1p1 receptor agonist and crystal form thereof, and pharmaceutical composition
AssigneeSuzhou Connect Biopharmaceuticals, Ltd.
InventorsWei ZHENG, Wubin PAN, Jiawang GUO
Life of this patent
Estimating the term…
Abstract
Disclosed in the present application are a salt form and a crystal form of an S1P1 receptor mediated disease or symptom drug 1-{2-fluoro-4-[5-(4-isobutylphenyl)-1,2,4-oxadiazole-3-yl]benzyl}-3-azetidinecarboxylic acid (formula A). Also disclosed in the present invention are a preparation method for the salt form or the crystal form, a pharmaceutical composition of the salt form or the crystal form, and use of the salt form or the crystal form in the preparation of a drug for treating and/or preventing an S1P1 receptor mediated disease or symptom.
Claims21
A sodium salt of a compound represented by formula A, having a structure represented by the following formula A:
A sulfate of a compound represented by formula A, having a structure represented by the following formula A:
A maleate of a compound represented by formula A, having a structure represented by the following formula A:
Dependencies are inferred from the claim text.