Substrate for nucleic acid amplification, and method for manufacturing same
AssigneeKorea Research Institute of Bioscience and Biotechnology
InventorsOh Seok KWON, Tai Hwan HA, Kyung Ho KIM, Jin Yeong KIM, Seon Joo PARK, Seong Eun SEO
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Abstract
The present invention relates to a substrate for nucleic acid amplification, and a method for manufacturing same, the substrate for rapid and accurate PCR analysis comprising: a transparent substrate; a micro-patterned metal layer formed on the transparent substrate; an N-heterocyclic carbene compound having one end annealed to the surface of the micro-patterned metal layer; and a primer immobilized on the other end of the N-heterocyclic carbene compound.
Claims18
A substrate for nucleic acid amplification, comprising:
- a transparent matrix;
- a micro-patterned metal layer formed on the transparent matrix;
- an N-heterocyclic carbene compound having one end bonded to the surface of the micro-patterned metal layer;
- and
- a primer immobilized on the other end of the N-heterocyclic carbene compound.
A method for manufacturing a substrate for nucleic acid amplification, the method comprising:
- forming a micro-patterned metal layer on a transparent matrix;
- introducing one end of an N-heterocyclic carbene compound onto the surface of the micro-patterned metal layer;
- and
- immobilizing a primer on the other end of the N-heterocyclic carbene compound.
Dependencies are inferred from the claim text.