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US 2021/0228722 A1Published application
Quinoline derivative-containing pharmaceutical composition
AssigneeEisai R&D Management Co., Ltd.
InventorMasashi Bando
Life of this patent
Estimating the term…
Abstract
A pharmaceutical composition comprising a compound represented by the formula (I) or pharmaceutically acceptable salt thereof or solvate thereof, and a basic substance is excellent in dissolution, is stable even after a long term storage, and is useful as a preventive or therapeutic agent against a tumor: wherein, R1 is a hydrogen atom, a C1-6 alkyl group or a C3-8 cycloalkyl group; and R2 is a hydrogen atom or a methoxy group.
Claims13
-12. (canceled)
A pharmaceutical composition, comprising:
- (1) a compound represented by formula (I), or a pharmaceutically acceptable salt thereof:
- wherein R1 is a hydrogen atom, a C1-6 alkyl group, or a C3-8 cycloalkyl group;
- and R2 represents a hydrogen atom or a methoxy group;
- (2) an alkaline earth metal carbonate;
- and
- (3) a disintegrating agent.
3 more elements
A pharmaceutical composition, comprising:
- (1) 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide methanesulfonate;
- (2) an alkaline earth metal carbonate;
- and
- (3) a disintegrating agent.
1 more element
Dependencies are inferred from the claim text.