N vivo delivery system of the genome dna modifying enzymes and the use thereof
OwnerSylwia BOBIS-WOZOWICZ, Ewa ZUBA-SURMA +1inventors
InventorsSylwia BOBIS-WOZOWICZ, Ewa ZUBA-SURMA, Toni CATHOMEN
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Abstract
The present invention relates to the in vivo delivery system of the DNA modifying enzymes comprising the stem cells-derived extracellular vesicles collected in serum-free conditions, characterized in that the said extracellular vesicles are the population of extracellular vesicles defined by the expression of surface markers. Moreover, the present invention is dedicated for use in a treatment of a genetic disease and/or disorder.
Claims21
In vivo delivery system of the DNA modifying enzymes comprising the stem cells-derived extracellular vesicles collected in serum-free conditions, characterized in that the said extracellular vesicles are the population of extracellular vesicles defined by the expression of surface markers.
The delivery system as defined in any of previous claims for use in a treatment of a genetic disease and/or disorder.
Dependencies are inferred from the claim text.