Method of using cyclodextrin
AssigneeL&F Research LLC
InventorsAlessia Fornoni, Sandra Merscher-Gomez
Life of this patent
Estimating the term…
Abstract
Described are methods for using cyclodextrin to treat, inhibit, prevent, ameliorate, or cure diabetes or conditions relating to diabetes.
Claims21
A method for treating or reducing the progression of a condition selected from the group consisting of diabetes (type 1), diabetes (type 2), prediabetes, obesity, metabolic syndrome, diabetic nephropathy, diabetic kidney disease, obesity related glomerulopathy, diabetic neuropathy, diabetic retinopathy, diabetes-related microvascular complication, diabetes-related macrovascular complications, atherosclerosis, peripheral vascular disease, coronary artery diseases, congestive heart failure, cardiac hypertrophy, myocardial infarction, endothelial dysfunction and hypertension, stroke, cerebrovascular accident, myocardial infarction, heart attack, cardiovascular accidents, fatty liver, steatohepatitis, NASH, and insulin resistance in a patient in need thereof, said method comprising administering to the patient an effective amount of a compound selected from the group consisting of a cyclodextrin as an active agent, a modulator of ABCA 1, a recombinant ApoA 1, an ApoA 1 mimetic peptide, a modulator of SMPDL3b, and an HDL mimetic.
(canceled)
(canceled)
A composition for treating, inhibiting, preventing, or ameliorating a symptom or related condition caused by cellular accumulation of cholesterol, wherein the composition consists essentially of an effective amount of a cyclodextrin as an active pharmaceutical agent, and optionally one or more pharmaceutically acceptable excipients or vehicles.
An article of manufacture comprising a composition in a container, said composition comprising at least one cyclodextrin as an active agent, wherein the container is packaged with written instruction for use of the composition for treatment of a condition caused by, or symptom resulting from, cellular or plasma membrane accumulation of lipid.
Dependencies are inferred from the claim text.