Method of treating cns disorders with neurosteroids and gabaergic compounds
AssigneesSage Therapeutics, Inc., Trustees of Tufts College
InventorsMichael Andrew Ackley, James J. Doherty, Stephen James Moss, Manasa Lakshmi Parakala, Paul A. Davies
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Abstract
Provided herein are methods, therapeutic agents and composition for treating a CNS-related disorder.
Claims37
A method for treating a CNS-related condition or disorder in a subject in need thereof, the method comprising administering to the subject a membrane progesterone receptor (mPR) agonist, wherein the mPR agonist is not progesterone, 5α-DHP, allopregnanolone or testosterone.
A method for treating a CNS-related condition or disorder in a subject in need thereof, comprising administering to the subject
- a) a membrane progesterone receptor (mPR) agonist;
- and
- b) a GABAergic modulator.
37-72. (canceled)
Dependencies are inferred from the claim text.