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US 2021/0228508 A1Published application
Compositions and methods thereof
AssigneeEXCIVA GmbH
InventorsSreenivasarao Vepachedu, Hans J. Moebius, Anton Bespalov
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Abstract
Compounds of Formula I or enantiomers thereof, metabolites thereof, derivatives thereof, deuterated derivatives thereof, prodrugs thereof, pharmaceutically acceptable salts thereof, N-oxides thereof, or a combination thereof, processes and intermediates for preparation thereof, compositions thereof, and uses thereof, are provided.
Claims2
A compound having of Formula I:
- wherein,
- R1, R2, and R3 are C1-10 alkyl, C3-10 cycloalkyl, C5-10 aryl, or C5-10 heteroaryl;
- X is a bond, or C1-10 alkyl, or —CO—C1-10 alkyl;
- R4 is NH—R5, S—R5, O—R5, —CO—R5, or —CO—O—R5 wherein R5 is an acyl radical;
- wherein the compound is selected from the group consisting of:
- or an enantiomer thereof, metabolite thereof, deuterated derivative thereof, halogenated derivative thereof, prodrug thereof, pharmaceutically acceptable salt thereof, N-oxide thereof, or a combination thereof.
3 more elements
Dependencies are inferred from the claim text.