Compositions Containing Verteporfin, Ribavirin, Gemcitabine, or Combinations Thereof and Methods of Use for Treating COVID-19, Cancer, or Non Cancer Diseases
OwnerMatthew McLeayinventor
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OwnerMatthew McLeayinventor
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Disclosed are pharmaceutical formulations and methods using Verteporfin Ribavirin and/or Gemcitabine for use in the treatment of diseases by various routes of administration including inhalation, intratumoral, topical and/or systemic injection administration. This invention relates more specifically to the use of Verteporfin, Ribavirin, Gemcitabine, and/or combinations thereof as an inhaled dry powder treatment for COVID-19 and/or other lung infections, cancer and other non-cancer applications, which may be followed by other treatment regimens including radiation therapy, photodynamic therapy, and/or sonodynamic therapy. These pharmaceutical compositions containing one or more of Verteporfin, Ribavirin, and Gemcitabine may be included in pharmaceutical kits containing the compositions, and to methods for the treatment of cancer and non-cancer diseases with the active agents of the pharmaceutical compositions. The administering of Verteporfin alone or in combination with Ribavirin and Gemcitabine may be followed or co-administered with photodynamic and/or sonodynamic therapy (PDT/SDT).
A method of treating a lung disease in a patient in need thereof comprising administering to a lung of said patient by inhalation an aerosol composition comprising ribavirin, verteporfin, and an excipient.
A method of treating lung cancer in a patient in need thereof comprising administering to a lung of said patient by inhalation an aerosol composition comprising ribavirin and an excipient.
A method of treating a SARS-CoV-2 lung infection in a patient in need thereof comprising administering to a lung of said patient by inhalation an aerosol composition comprising ribavirin and an excipient.
Dependencies are inferred from the claim text.