Pulse generator for irreversible electroporation with switchable pulse application

A medical apparatus for irreversible electroporation, the apparatus comprising:

• a probe configured for insertion into a body of a patient and comprising an array of electrodes disposed along the probe and configured to contact tissue within the body;
• and
• an electrical signal generator configured to apply sequences of bipolar pulses over one or more trios of the electrodes, each trio comprising first, second and third neighboring electrodes, such that the second electrode is disposed between and adjacent to the first and third electrodes,
• wherein while the probe contacts the tissue, the electrical signal generator applies the sequences of the bipolar pulses between the first and second electrodes during one or more first time intervals, and between the second and third electrodes during one or more second time intervals, and between the first and third electrodes during one or more third time intervals, wherein the first, second and third time intervals are mutually disjoint.