REGION OF INTEREST FOCAL SOURCE DETECTION USING COMPARISONS OF R-S WAVE MAGNITUDES AND LATs OF RS COMPLEXES

A system comprising:

• a plurality of sensors each configured to acquire one of a plurality of electro-cardiogram (ECG) signals over time representing electrical activity of one of a plurality of different areas of a heart, each ECG signal comprising an R wave and an S wave;
• and
• a processing device comprising one or more processors configured to:
• determine local activation times (LATs) of each ECG signal, each LAT of a respective ECG signal corresponding to acquired electrical activity at a different point in time;
• identify a plurality of LATs determined to be part of a same cardiac activation cycle;
• generate first mapping information for visually indicating, at locations on a local activation time (LAT) map for each ECG signal, a number of instances, over a period of time that includes multiple cardiac activation cycles, in which at least one of the plurality of LATS is an earliest LAT;
• and
• generate second mapping information for visually indicating, at locations on an R-S map corresponding to the same locations on the LAT map, sizes of R-to-S ratios for each ECG signal in the period of time that includes multiple cardiac activation cycles, each R-to-S ratio comprising a ratio of a magnitude of the R wave to a magnitude of the S wave,
• wherein potential focal sources of activation of the heart are identified based on the visually indicated number of times at each location on the LAT map and the visually indicated sizes of the R-to-S ratios at each corresponding location on the R-S map.

A non-transitory computer readable storage medium in which computer program instructions are stored, which instructions, when executed by a computer, cause the computer to perform the steps of:

• acquiring, via a plurality of sensors, electro-cardiogram (ECG) signals over time, each ECG signal acquired via one of the plurality of sensors and representing electrical activity of one of a plurality of different areas of a heart, each ECG signal comprising at least an R wave and an S wave;
• determining local activation times (LATs) of each ECG signal, each LAT of a respective ECG signal corresponding to acquired electrical activity at a different point in time;
• identifying a plurality of LATs determined to be part of a same cardiac activation cycle;
• generating first mapping information for visually indicating, at locations on a local activation time (LAT) map for each ECG signal, a number of instances, over a period of time that includes multiple cardiac activation cycles, in which at least one of the plurality of LATS is an earliest LAT;
• and
• generating second mapping information for visually indicating, at locations on an R-S map corresponding to the same locations on the LAT map, sizes of R-to-S ratios for each ECG signal in the period of time that includes multiple cardiac activation cycles, each R-to-S ratio comprising a ratio of a magnitude of the R wave to a magnitude of the S wave,
• wherein, potential focal sources of activation of the heart are identified based on the visually indicated number of times at each location on the LAT map and the visually indicated sizes of the R-to-S ratios at each corresponding location on the R-S map.