Vaccine Composition for Preventing or Treating Diseases Caused by Severe Fever with Thrombocytopenia Syndrome (SFTS) Viral Infection
AssigneesKorea Advanced Institute of Science and Technology, Geneone Life Science, Inc.
InventorsSu Hyung Park, Jeong Eun Kwak, Moon Sup Jeong, Jin Ah Kwon, Hyo Jin Lee, Young Ran Cho, Ji Hye Koo, Joel Maslow, Byung Mun Cho, Young Kun Park
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Abstract
The present disclosure relates to a vaccine composition for preventing or treating infectious diseases caused by severe fever with thrombocytopenia syndrome (SFTS) virus.
Claims20
An antigenic composition comprising, as an active ingredient, any one or more selected from the group consisting of:
- a first recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 287, or which is encoded by a first recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 286;
- a second recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 289, or which is encoded by a second recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 288;
- a third recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 291, or which is encoded by a third recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 290;
- a fourth recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 293, or which is encoded by a fourth recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 292;
- and
- a fifth recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 295, or which is encoded by a fifth recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 294.
A vaccine comprising, as an active ingredient, any one or more selected from the group consisting of:
- a first recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 287, or which is encoded by a first recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 286;
- a second recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 289, or which is encoded by a second recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 288;
- a third recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 291, or which is encoded by a third recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 290;
- a fourth recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 293, or which is encoded by a fourth recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 292;
- and
- a fifth recombinant peptide which comprises an amino acid sequence represented by SEQ ID NO:
- 295, or which is encoded by a fifth recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 294.
An expression vector comprising any one or more recombinant DNAs selected from the group consisting of:
- a first recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 286;
- a second recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 288;
- a third recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 290;
- a fourth recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 292;
- and
- a fifth recombinant DNA comprising a nucleotide sequence represented by SEQ ID NO:
- 294.
Dependencies are inferred from the claim text.