Pest control compositions and uses thereof
AssigneeFlagship Pioneering Innovations VI, LLC
InventorsMaria Helena Christine VAN ROOIJEN, Barry Andrew MARTIN, Hok Hei TAM, Jonathan FRIEDLANDER, Ignacio MARTINEZ, Nataliya Vladimirovna NUKOLOVA, Simon SCHWIZER, Daniel Garcia CABANILLAS
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Abstract
Disclosed herein are pest control, e.g., biopesticide or biorepellent, compositions including a plurality of plant messenger packs (e.g., including a plant extracellular vesicle (EV), or segment, portion, or extract thereof) that are useful in methods for decreasing the fitness of pests (e.g., agriculture pests) and/or increasing the fitness of a plant.
Claims92
A pest control composition comprising a plurality of PMPs, wherein each of the plurality of PMPs comprises a heterologous pesticidal agent and wherein the composition is formulated for delivery to a plant or a plant pest.
A pest control composition comprising a plurality of PMPs, wherein the PMPs are isolated from a plant by a process which comprises the steps of:
- (a) providing an initial sample from a plant, or a part thereof, wherein the plant or part thereof comprises EVs;
- (b) isolating a crude PMP fraction from the initial sample, wherein the crude PMP fraction has a decreased level of at least one contaminant or undesired component from the plant or part thereof relative to the level in the initial sample;
- (c) purifying the crude PMP fraction, thereby producing a plurality of pure PMPs, wherein the plurality of pure PMPs have a decreased level of at least one contaminant or undesired component from the plant or part thereof relative to the level in the crude EV fraction;
- (d) loading the plurality of pure PMPs with a pest control agent;
- and
- (e) formulating the PMPs of step (d) for delivery to a plant or a plant pest.
A method of treating a plant having a fungal infection, wherein the method comprises delivering to the plant a pest control composition comprising a plurality of PMPs.
A method of treating a plant having a fungal infection, wherein the method comprises delivering to the plant a pest control composition comprising a plurality of PMPs, and wherein each of the plurality of PMPs comprises an antifungal agent.
A method of treating a plant having a bacterial infection, wherein the method comprises delivering to the plant a pest control composition comprising a plurality of PMPs.
A method of treating a plant having a bacterial infection, wherein the method comprises delivering to the plant a pest control composition comprising a plurality of PMPs, and wherein each of the plurality of PMPs comprises an antibacterial agent.
A method of decreasing the fitness of an insect plant pest, wherein the method comprises delivering to the insect plant pest a pest control composition comprising a plurality of PMPs.
A method of decreasing the fitness of an insect plant pest, wherein the method comprises delivering to the insect plant pest a pest control composition comprising a plurality of PMPs, and wherein each of the plurality of PMPs comprises an insecticidal agent.
A method of decreasing the fitness of a nematode plant pest, wherein the method comprises delivering to the nematode plant pest a pest control composition comprising a plurality of PMPs.
A method of decreasing the fitness of a nematode plant pest, wherein the method comprises delivering to the nematode plant pest a pest control composition comprising a plurality of PMPs, and wherein each of the plurality of PMPs comprises a nematicidal agent.
A method of decreasing the fitness of a weed, wherein the method comprises delivering to the weed a pest control composition comprising a plurality of PMPs.
A method of decreasing the fitness of a weed, wherein the method comprises delivering to the weed a pest control composition comprising a plurality of PMPs, and wherein each of the plurality of PMPs comprises an herbicidal agent.
Dependencies are inferred from the claim text.