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US 2021/0215591 A1Published application
Devices for generating monodisperse droplets from a bulk liquid
AssigneeFluent Biosciences Inc.
InventorsKristina Fontanez, Robert Meltzer, Yi Xue, Sepehr Kiani
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Abstract
The invention provides devices that generate monodisperse droplets from a bulk liquid. The devices include a shearing mechanism, a holder for a vessel containing a liquid, and an optical system that transmit light to, and detects light from, liquid in the vessel. The invention also provides methods of using such devices to produce monodisperse droplets.
Claims20
A device comprising:
- a shearing mechanism for applying shearing energy to a liquid contained in at least one vessel;
- a holder coupled to the shearing mechanism and configured to secure the at least one vessel;
- and
- an optical system comprising:
- a light source positioned to transmit light to the liquid contained in the at least one vessel, and
- a photodetector positioned to sense the transmitted light from the liquid contained in the at least one vessel.
3 more elements
A method for generating an emulsion comprising substantially monodisperse droplets, the method comprising:
- contacting at least one vessel containing a liquid with a device comprising:
- a shearing mechanism, and
- a holder configured to secure the at least one vessel and coupled to the shearing mechanism;
- and
- applying shearing energy from the shearing mechanism to the liquid, thereby generating an emulsion comprising substantially monodisperse droplets.
2 more elements
Dependencies are inferred from the claim text.