US 2021/0214316 A1Published application

Anti-cancer nuclear hormone receptor-targeting compounds

AssigneeNuvation Bio Inc.

InventorsSon Minh Pham, Jayakanth Kankanala, Jeremy Pettigrew, Christopher Paul Miller

Life of this patent

Estimating the term…

Abstract

The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

Claims24

Dependent claims

A compound of Formula A-L-B, wherein:

A is A1, A2, A3, or A4, wherein:
A1 is
A2 is
A3 is
and
A4 is
L is L1, L2, L3, L4, L5, L6, L7, L8, L9, L10, L11, L12, L13, L14, L15, L16, L17, L18, L19, L20, L21, L22, L23, L24, L25, L26, L27, L28, L29, L30, L31, L32, L33, L34, L35, L36, L37, L38, L39, L40, L41, L42, L43, L44, L45, or L46, wherein:
L1 is
L2 is
L3 is
L4 is
L5 is
L6 is
L7 is
L8 is
L9 is
L10 is
L11 is
L12 is
L13 is
L14 is
L15 is
L16 is
L17 is
L18 is
L19 is
L20 is
L21 is
L22 is
L23 is
L24 is
L25 is
L26 is
L27 is
L28 is
L29 is
L30 is
L31 is
L32 is
L33 is
L34 is
L35 is
L36 is
L37 is
L38 is
L39 is
L40 is
L41 is
L42 is
L43 is
L44 is
L45 is
and
L46 is
and;
B is B1, B2, B3, B4, B5, B6, B7, B8, B9, B10, B11, B12, B13, B14, B15, B16, B17, B18, or B19, wherein:
B1 is
B2 is
B3 is
B4 is
B5 is
B6 is
B7 is
B8 is
B9 is
B10 is
B11 is
B12 is
B13 is
B14 is
B15 is
B16 is
B17 is
B18 is
and
B19 is
and further wherein the “*” in each A and L moiety denotes a covalent bond therebetween, and the wavy line in each L and B denotes a covalent bond therebetween;
wherein the compound of Formula A-L-B is selected from:
A1-L1-B1
A1-L1-B2
A1-L1-B3
A1-L1-B4
A1-L1-B5
A1-L1-B6
A1-L1-B7
A1-L1-B8
A1-L1-B9
A1-L1-B10
A1-L1-B11
A1-L1-B12
A1-L1-B13
A1-L2-B1
A1-L2-B2
A1-L2-B3
A1-L2-B4
A1-L2-B5
A1-L2-B6
A1-L2-B7
A1-L2-B8
A1-L2-B9
A1-L2-B10
A1-L2-B11
A1-L2-B12
A1-L2-B13
A1-L3-B1
A1-L3-B2
A1-L3-B3
A1-L3-B4
A1-L3-B5
A1-L3-B6
A1-L3-B7
A1-L3-B8
A1-L3-B9
A1-L3-B10
A1-L3-B11
A1-L3-B12
A1-L3-B13
A1-L4-B1
A1-L4-B2
A1-L4-B3
A1-L4-B4
A1-L4-B5
A1-L4-B6
A1-L4-B7
A1-L4-B8
A1-L4-B9
A1-L4-B10
A1-L4-B11
A1-L4-B12
A1-L4-B13
A1-L5-B1
A1-L5-B2
A1-L5-B3
A1-L5-B4
A1-L5-B5
A1-L5-B6
A1-L5-B7
A1-L5-B8
A1-L5-B9
A1-L5-B10
A1-L5-B11
A1-L5-B12
A1-L5-B13
A1-L6-B1
A1-L6-B2
A1-L6-B3
A1-L6-B4
A1-L6-B5
A1-L6-B6
A1-L6-B7
A1-L6-B8
A1-L6-B9
A1-L6-B10
A1-L6-B11
A1-L6-B12
A1-L6-B13
A1-L7-B1
A1-L7-B2
A1-L7-B3
A1-L7-B4
A1-L7-B5
A1-L7-B6
A1-L7-B7
A1-L7-B8
A1-L7-B9
A1-L7-B10
A1-L7-B11
A1-L7-B12
A1-L7-B13
A1-L8-B1
A1-L8-B2
A1-L8-B3
A1-L8-B4
A1-L8-B5
A1-L8-B6
A1-L8-B7
A1-L8-B8
A1-L8-B9
A1-L8-B10
A1-L8-B11
A1-L8-B12
A1-L8-B13
A1-L9-B1
A1-L9-B2
A1-L9-B3
A1-L9-B7
A1-L9-B8
A1-L9-B9
A1-L9-B11
A1-L9-B13
A1-L20-B1
A1-L20-B2
A1-L20-B3
A1-L20-B4
A1-L20-B5
A1-L20-B6
A1-L20-B7
A1-L20-B8
A1-L20-B9
A1-L20-B10
A1-L20-B11
A1-L20-B12
A1-L20-B13
A1-L21-B1
A1-L21-B2
A1-L21-B3
A1-L21-B4
A1-L21-B5
A1-L21-B6
A1-L21-B7
A1-L21-B8
A1-L21-B9
A1-L21-B10
A1-L21-B11
A1-L21-B12
A1-L21-B13
A1-L22-B1
A1-L22-B2
A1-L22-B3
A1-L22-B4
A1-L22-B5
A1-L22-B6
A1-L22-B7
A1-L22-B8
A1-L22-B9
A1-L22-B10
A1-L22-B11
A1-L22-B12
A1-L22-B13
A1-L23-B1
A1-L23-B2
A1-L23-B3
A1-L23-B4
A1-L23-B5
A1-L23-B6
A1-L23-B7
A1-L23-B8
A1-L23-B9
A1-L23-B10
A1-L23-B11
A1-L23-B12
A1-L23-B13
A1-L24-B1
A1-L24-B2
A1-L24-B3
A1-L24-B4
A1-L24-B5
A1-L24-B6
A1-L24-B7
A1-L24-B8
A1-L24-B9
A1-L24-B10
A1-L24-B11
A1-L24-B12
A1-L24-B13
A1-L30-B1
A1-L30-B2
A1-L30-B3
A1-L30-B4
A1-L30-B5
A1-L30-B6
A1-L30-B7
A1-L30-B8
A1-L30-B9
A1-L30-B10
A1-L30-B11
A1-L30-B12
A1-L30-B13
A1-L31-B1
A1-L31-B2
A1-L31-B3
A1-L31-B4
A1-L31-B5
A1-L31-B6
A1-L31-B7
A1-L31-B8
A1-L31-B9
A1-L31-B10
A1-L31-B11
A1-L31-B12
A1-L31-B13
A1-L32-B1
A1-L32-B2
A1-L32-B3
A1-L32-B7
A1-L32-B8
A1-L32-B9
A1-L32-B11
A1-L32-B13
A1-L39-B1
A1-L39-B2
A1-L39-B3
A1-L39-B4
A1-L39-B5
A1-L39-B6
A1-L39-B7
A1-L39-B8
A1-L39-B9
A1-L39-B10
A1-L39-B11
A1-L39-B12
A1-L39-B13
A1-L40-B1
A1-L40-B2
A1-L40-B3
A1-L40-B4
A1-L40-B5
A1-L40-B6
A1-L40-B7
A1-L40-B8
A1-L40-B9
A1-L40-B10
A1-L40-B11
A1-L40-B12
A1-L40-B13
A1-L41-B1
A1-L41-B2
A1-L41-B3
A1-L41-B4
A1-L41-B5
A1-L41-B6
A1-L41-B7
A1-L41-B8
A1-L41-B9
A1-L41-B10
A1-L41-B11
A1-L41-B12
A1-L41-B13
A1-L42-B1
A1-L42-B2
A1-L42-B3
A1-L42-B4
A1-L42-B5
A1-L42-B6
A1-L42-B7
A1-L42-B8
A1-L42-B9
A1-L42-B10
A1-L42-B11
A1-L42-B12
A1-L42-B13
A1-L43-B1
A1-L43-B2
A1-L43-B3
A1-L43-B4
A1-L43-B5
A1-L43-B6
A1-L43-B7
A1-L43-B8
A1-L43-B9
A1-L43-B10
A1-L43-B11
A1-L43-B12
A1-L43-B13
A1-L44-B1
A1-L44-B2
A1-L44-B3
A1-L44-B7
A1-L44-B8
A1-L44-B9
A1-L44-B11
A1-L44-B13
A2-L1-B1
A2-L1-B2
A2-L1-B3
A2-L1-B4
A2-L1-B5
A2-L1-B6
A2-L1-B7
A2-L1-B8
A2-L1-B9
A2-L1-B10
A2-L1-B11
A2-L1-B12
A2-L1-B13
A2-L2-B1
A2-L2-B2
A2-L2-B3
A2-L2-B4
A2-L2-B5
A2-L2-B6
A2-L2-B7
A2-L2-B8
A2-L2-B9
A2-L2-B10
A2-L2-B11
A2-L2-B12
A2-L2-B13
A2-L3-B1
A2-L3-B2
A2-L3-B3
A2-L3-B4
A2-L3-B5
A2-L3-B6
A2-L3-B7
A2-L3-B8
A2-L3-B9
A2-L3-B10
A2-L3-B11
A2-L3-B12
A2-L3-B13
A2-L4-B1
A2-L4-B2
A2-L4-B3
A2-L4-B4
A2-L4-B5
A2-L4-B6
A2-L4-B7
A2-L4-B8
A2-L4-B9
A2-L4-B10
A2-L4-B11
A2-L4-B12
A2-L4-B13
A2-L5-B1
A2-L5-B2
A2-L5-B3
A2-L5-B4
A2-L5-B5
A2-L5-B6
A2-L5-B7
A2-L5-B8
A2-L5-B9
A2-L5-B10
A2-L5-B11
A2-L5-B12
A2-L5-B13
A2-L6-B1
A2-L6-B2
A2-L6-B3
A2-L6-B4
A2-L6-B5
A2-L6-B6
A2-L6-B7
A2-L6-B8
A2-L6-B9
A2-L6-B10
A2-L6-B11
A2-L6-B12
A2-L6-B13
A2-L7-B1
A2-L7-B2
A2-L7-B3
A2-L7-B4
A2-L7-B5
A2-L7-B6
A2-L7-B7
A2-L7-B8
A2-L7-B9
A2-L7-B10
A2-L7-B11
A2-L7-B12
A2-L7-B13
A2-L8-B1
A2-L8-B2
A2-L8-B3
A2-L8-B4
A2-L8-B5
A2-L8-B6
A2-L8-B7
A2-L8-B8
A2-L8-B9
A2-L8-B10
A2-L8-B11
A2-L8-B12
A2-L8-B13
A2-L9-B1
A2-L9-B2
A2-L9-B3
A2-L9-B7
A2-L9-B8
A2-L9-B9
A2-L9-B11
A2-L9-B13
A2-L10-B1
A2-L10-B2
A2-L10-B3
A2-L10-B4
A2-L10-B5
A2-L10-B6
A2-L10-B7
A2-L10-B8
A2-L10-B9
A2-L10-B10
A2-L10-B11
A2-L10-B12
A2-L10-B13
A2-L11-B1
A2-L11-B2
A2-L11-B3
A2-L11-B4
A2-L11-B5
A2-L11-B6
A2-L11-B7
A2-L11-B8
A2-L11-B9
A2-L11-B10
A2-L11-B11
A2-L11-B12
A2-L11-B13
A2-L12-B1
A2-L12-B2
A2-L12-B3
A2-L12-B7
A2-L12-B8
A2-L12-B9
A2-L12-B11
A2-L12-B13
A2-L13-B1
A2-L13-B2
A2-L13-B3
A2-L13-B4
A2-L13-B5
A2-L13-B6
A2-L13-B7
A2-L13-B8
A2-L13-B9
A2-L13-B10
A2-L13-B11
A2-L13-B12
A2-L13-B13
A2-L14-B1
A2-L14-B2
A2-L14-B3
A2-L14-B4
A2-L14-B5
A2-L14-B6
A2-L14-B7
A2-L14-B8
A2-L14-B9
A2-L14-B10
A2-L14-B11
A2-L14-B12
A2-L14-B13
A2-L15-B1
A2-L15-B2
A2-L15-B3
A2-L15-B4
A2-L15-B5
A2-L15-B6
A2-L15-B7
A2-L15-B8
A2-L15-B9
A2-L15-B10
A2-L15-B11
A2-L15-B12
A2-L15-B13
A2-L16-B1
A2-L16-B2
A2-L16-B3
A2-L16-B4
A2-L16-B5
A2-L16-B6
A2-L16-B7
A2-L16-B8
A2-L16-B9
A2-L16-B10
A2-L16-B11
A2-L16-B12
A2-L16-B13
A2-L17-B1
A2-L17-B2
A2-L17-B3
A2-L17-B7
A2-L17-B8
A2-L17-B9
A2-L17-B11
A2-L17-B13
A2-L18-B1
A2-L18-B2
A2-L18-B3
A2-L18-B4
A2-L18-B5
A2-L18-B6
A2-L18-B7
A2-L18-B8
A2-L18-B9
A2-L18-B10
A2-L18-B11
A2-L18-B12
A2-L18-B13
A2-L19-B1
A2-L19-B2
A2-L19-B3
A2-L19-B4
A2-L19-B5
A2-L19-B6
A2-L19-B7
A2-L19-B8
A2-L19-B9
A2-L19-B10
A2-L19-B11
A2-L19-B12
A2-L19-B13
A2-L20-B1
A2-L20-B2
A2-L20-B3
A2-L20-B4
A2-L20-B5
A2-L20-B6
A2-L20-B7
A2-L20-B8
A2-L20-B9
A2-L20-B10
A2-L20-B11
A2-L20-B12
A2-L20-B13
A2-L21-B1
A2-L21-B2
A2-L21-B3
A2-L21-B4
A2-L21-B5
A2-L21-B6
A2-L21-B7
A2-L21-B8
A2-L21-B9
A2-L21-B10
A2-L21-B11
A2-L21-B12
A2-L21-B13
A2-L22-B1
A2-L22-B2
A2-L22-B3
A2-L22-B4
A2-L22-B5
A2-L22-B6
A2-L22-B7
A2-L22-B8
A2-L22-B9
A2-L22-B10
A2-L22-B11
A2-L22-B12
A2-L22-B13
A2-L23-B1
A2-L23-B2
A2-L23-B3
A2-L23-B4
A2-L23-B5
A2-L23-B6
A2-L23-B7
A2-L23-B8
A2-L23-B9
A2-L23-B10
A2-L23-B11
A2-L23-B12
A2-L23-B13
A2-L24-B1
A2-L24-B2
A2-L24-B3
A2-L24-B4
A2-L24-B5
A2-L24-B6
A2-L24-B7
A2-L24-B8
A2-L24-B9
A2-L24-B10
A2-L24-B11
A2-L24-B12
A2-L24-B13
A2-L25-B1
A2-L25-B2
A2-L25-B3
A2-L25-B4
A2-L25-B5
A2-L25-B6
A2-L25-B7
A2-L25-B8
A2-L25-B9
A2-L25-B10
A2-L25-B11
A2-L25-B12
A2-L25-B13
A2-L26-B1
A2-L26-B2
A2-L26-B3
A2-L26-B4
A2-L26-B5
A2-L26-B6
A2-L26-B7
A2-L26-B8
A2-L26-B9
A2-L26-B10
A2-L26-B11
A2-L26-B12
A2-L26-B13
A2-L27-B1
A2-L27-B2
A2-L27-B3
A2-L27-B4
A2-L27-B5
A2-L27-B6
A2-L27-B7
A2-L27-B8
A2-L27-B9
A2-L27-B10
A2-L27-B11
A2-L27-B12
A2-L27-B13
A2-L28-B1
A2-L28-B2
A2-L28-B3
A2-L28-B4
A2-L28-B5
A2-L28-B6
A2-L28-B7
A2-L28-B8
A2-L28-B9
A2-L28-B10
A2-L28-B11
A2-L28-B12
A2-L28-B13
A2-L29-B1
A2-L29-B2
A2-L29-B3
A2-L29-B4
A2-L29-B5
A2-L29-B6
A2-L29-B7
A2-L29-B8
A2-L29-B9
A2-L29-B10
A2-L29-B11
A2-L29-B12
A2-L29-B13
A2-L30-B1
A2-L30-B2
A2-L30-B3
A2-L30-B4
A2-L30-B5
A2-L30-B6
A2-L30-B7
A2-L30-B8
A2-L30-B9
A2-L30-B10
A2-L30-B11
A2-L30-B12
A2-L30-B13
A2-L31-B1
A2-L31-B2
A2-L31-B3
A2-L31-B4
A2-L31-B5
A2-L31-B6
A2-L31-B7
A2-L31-B8
A2-L31-B9
A2-L31-B10
A2-L31-B11
A2-L31-B12
A2-L31-B13
A2-L32-B1
A2-L32-B2
A2-L32-B3
A2-L32-B7
A2-L32-B8
A2-L32-B9
A2-L32-B11
A2-L32-B13
A2-L33-B1
A2-L33-B2
A2-L33-B3
A2-L33-B4
A2-L33-B5
A2-L33-B6
A2-L33-B7
A2-L33-B8
A2-L33-B9
A2-L33-B10
A2-L33-B11
A2-L33-B12
A2-L33-B13
A2-L34-B1
A2-L34-B2
A2-L34-B3
A2-L34-B7
A2-L34-B8
A2-L34-B9
A2-L34-B11
A2-L34-B13
A2-L35-B1
A2-L35-B2
A2-L35-B3
A2-L35-B4
A2-L35-B5
A2-L35-B6
A2-L35-B7
A2-L35-B8
A2-L35-B9
A2-L35-B10
A2-L35-B11
A2-L35-B12
A2-L35-B13
A2-L36-B1
A2-L36-B2
A2-L36-B3
A2-L36-B4
A2-L36-B5
A2-L36-B6
A2-L36-B7
A2-L36-B8
A2-L36-B9
A2-L36-B10
A2-L36-B11
A2-L36-B12
A2-L36-B13
A2-L37-B1
A2-L37-B2
A2-L37-B3
A2-L37-B4
A2-L37-B5
A2-L37-B6
A2-L37-B7
A2-L37-B8
A2-L37-B9
A2-L37-B10
A2-L37-B11
A2-L37-B12
A2-L37-B13
A2-L38-B1
A2-L38-B2
A2-L38-B3
A2-L38-B4
A2-L38-B5
A2-L38-B6
A2-L38-B7
A2-L38-B8
A2-L38-B9
A2-L38-B10
A2-L38-B11
A2-L38-B12
A2-L38-B13
A2-L39-B1
A2-L39-B2
A2-L39-B3
A2-L39-B4
A2-L39-B5
A2-L39-B6
A2-L39-B7
A2-L39-B8
A2-L39-B9
A2-L39-B10
A2-L39-B11
A2-L39-B12
A2-L39-B13
A2-L40-B1
A2-L40-B2
A2-L40-B3
A2-L40-B4
A2-L40-B5
A2-L40-B6
A2-L40-B7
A2-L40-B8
A2-L40-B9
A2-L40-B10
A2-L40-B11
A2-L40-B12
A2-L40-B13
A2-L41-B1
A2-L41-B2
A2-L41-B3
A2-L41-B4
A2-L41-B5
A2-L41-B6
A2-L41-B7
A2-L41-B8
A2-L41-B9
A2-L41-B10
A2-L41-B11
A2-L41-B12
A2-L41-B13
A2-L42-B1
A2-L42-B2
A2-L42-B3
A2-L42-B4
A2-L42-B5
A2-L42-B6
A2-L42-B7
A2-L42-B8
A2-L42-B9
A2-L42-B10
A2-L42-B11
A2-L42-B12
A2-L42-B13
A2-L43-B1
A2-L43-B2
A2-L43-B3
A2-L43-B4
A2-L43-B5
A2-L43-B6
A2-L43-B7
A2-L43-B8
A2-L43-B9
A2-L43-B10
A2-L43-B11
A2-L43-B12
A2-L43-B13
A2-L44-B1
A2-L44-B2
A2-L44-B3
A2-L44-B7
A2-L44-B8
A2-L44-B9
A2-L44-B11
A2-L44-B13
A3-L1-B1
A3-L1-B2
A3-L1-B3
A3-L1-B4
A3-L1-B5
A3-L1-B6
A3-L1-B7
A3-L1-B8
A3-L1-B9
A3-L1-B10
A3-L1-B11
A3-L1-B12
A3-L1-B13
A3-L2-B1
A3-L2-B2
A3-L2-B3
A3-L2-B4
A3-L2-B5
A3-L2-B6
A3-L2-B7
A3-L2-B8
A3-L2-B9
A3-L2-B10
A3-L2-B11
A3-L2-B12
A3-L2-B13
A3-L3-B1
A3-L3-B2
A3-L3-B3
A3-L3-B4
A3-L3-B5
A3-L3-B6
A3-L3-B7
A3-L3-B8
A3-L3-B9
A3-L3-B10
A3-L3-B11
A3-L3-B12
A3-L3-B13
A3-L4-B1
A3-L4-B2
A3-L4-B3
A3-L4-B4
A3-L4-B5
A3-L4-B6
A3-L4-B7
A3-L4-B8
A3-L4-B9
A3-L4-B10
A3-L4-B11
A3-L4-B12
A3-L4-B13
A3-L5-B1
A3-L5-B2
A3-L5-B3
A3-L5-B4
A3-L5-B5
A3-L5-B6
A3-L5-B7
A3-L5-B8
A3-L5-B9
A3-L5-B10
A3-L5-B11
A3-L5-B12
A3-L5-B13
A3-L6-B1
A3-L6-B2
A3-L6-B3
A3-L6-B4
A3-L6-B5
A3-L6-B6
A3-L6-B7
A3-L6-B8
A3-L6-B9
A3-L6-B10
A3-L6-B11
A3-L6-B12
A3-L6-B13
A3-L7-B1
A3-L7-B2
A3-L7-B3
A3-L7-B4
A3-L7-B5
A3-L7-B6
A3-L7-B7
A3-L7-B8
A3-L7-B9
A3-L7-B10
A3-L7-B11
A3-L7-B12
A3-L7-B13
A3-L8-B1
A3-L8-B2
A3-L8-B3
A3-L8-B4
A3-L8-B5
A3-L8-B6
A3-L8-B7
A3-L8-B8
A3-L8-B9
A3-L8-B10
A3-L8-B11
A3-L8-B12
A3-L8-B13
A3-L9-B1
A3-L9-B2
A3-L9-B3
A3-L9-B7
A3-L9-B8
A3-L9-B9
A3-L9-B11
A3-L9-B13
A3-L10-B1
A3-L10-B2
A3-L10-B3
A3-L10-B4
A3-L10-B5
A3-L10-B6
A3-L10-B7
A3-L10-B8
A3-L10-B9
A3-L10-B10
A3-L10-B11
A3-L10-B12
A3-L10-B13
A3-L11-B1
A3-L11-B2
A3-L11-B3
A3-L11-B4
A3-L11-B5
A3-L11-B6
A3-L11-B7
A3-L11-B8
A3-L11-B9
A3-L11-B10
A3-L11-B11
A3-L11-B12
A3-L11-B13
A3-L12-B1
A3-L12-B2
A3-L12-B3
A3-L12-B7
A3-L12-B8
A3-L12-B9
A3-L12-B11
A3-L12-B13
A3-L13-B1
A3-L13-B2
A3-L13-B3
A3-L13-B4
A3-L13-B5
A3-L13-B6
A3-L13-B7
A3-L13-B8
A3-L13-B9
A3-L13-B10
A3-L13-B11
A3-L13-B12
A3-L13-B13
A3-L14-B1
A3-L14-B2
A3-L14-B3
A3-L14-B4
A3-L14-B5
A3-L14-B6
A3-L14-B7
A3-L14-B8
A3-L14-B9
A3-L14-B10
A3-L14-B11
A3-L14-B12
A3-L14-B13
A3-L15-B1
A3-L15-B2
A3-L15-B3
A3-L15-B4
A3-L15-B5
A3-L15-B6
A3-L15-B7
A3-L15-B8
A3-L15-B9
A3-L15-B10
A3-L15-B11
A3-L15-B12
A3-L15-B13
A3-L16-B1
A3-L16-B2
A3-L16-B3
A3-L16-B4
A3-L16-B5
A3-L16-B6
A3-L16-B7
A3-L16-B8
A3-L16-B9
A3-L16-B10
A3-L16-B11
A3-L16-B12
A3-L16-B13
A3-L17-B1
A3-L17-B2
A3-L17-B3
A3-L17-B7
A3-L17-B8
A3-L17-B9
A3-L17-B11
A3-L17-B13
A3-L18-B1
A3-L18-B2
A3-L18-B3
A3-L18-B4
A3-L18-B5
A3-L18-B6
A3-L18-B7
A3-L18-B8
A3-L18-B9
A3-L18-B10
A3-L18-B11
A3-L18-B12
A3-L18-B13
A3-L19-B1
A3-L19-B2
A3-L19-B3
A3-L19-B4
A3-L19-B5
A3-L19-B6
A3-L19-B7
A3-L19-B8
A3-L19-B9
A3-L19-B10
A3-L19-B11
A3-L19-B12
A3-L19-B13
A3-L20-B1
A3-L20-B2
A3-L20-B3
A3-L20-B4
A3-L20-B5
A3-L20-B6
A3-L20-B7
A3-L20-B8
A3-L20-B9
A3-L20-B10
A3-L20-B11
A3-L20-B12
A3-L20-B13
A3-L21-B1
A3-L21-B2
A3-L21-B3
A3-L21-B4
A3-L21-B5
A3-L21-B6
A3-L21-B7
A3-L21-B8
A3-L21-B9
A3-L21-B10
A3-L21-B11
A3-L21-B12
A3-L21-B13
A3-L22-B1
A3-L22-B2
A3-L22-B3
A3-L22-B4
A3-L22-B5
A3-L22-B6
A3-L22-B7
A3-L22-B8
A3-L22-B9
A3-L22-B10
A3-L22-B11
A3-L22-B12
A3-L22-B13
A3-L23-B1
A3-L23-B2
A3-L23-B3
A3-L23-B4
A3-L23-B5
A3-L23-B6
A3-L23-B7
A3-L23-B8
A3-L23-B9
A3-L23-B10
A3-L23-B11
A3-L23-B12
A3-L23-B13
A3-L24-B1
A3-L24-B2
A3-L24-B3
A3-L24-B4
A3-L24-B5
A3-L24-B6
A3-L24-B7
A3-L24-B8
A3-L24-B9
A3-L24-B10
A3-L24-B11
A3-L24-B12
A3-L24-B13
A3-L25-B1
A3-L25-B2
A3-L25-B3
A3-L25-B4
A3-L25-B5
A3-L25-B6
A3-L25-B7
A3-L25-B8
A3-L25-B9
A3-L25-B10
A3-L25-B11
A3-L25-B12
A3-L25-B13
A3-L26-B1
A3-L26-B2
A3-L26-B3
A3-L26-B4
A3-L26-B5
A3-L26-B6
A3-L26-B7
A3-L26-B8
A3-L26-B9
A3-L26-B10
A3-L26-B11
A3-L26-B12
A3-L26-B13
A3-L27-B1
A3-L27-B2
A3-L27-B3
A3-L27-B4
A3-L27-B5
A3-L27-B6
A3-L27-B7
A3-L27-B8
A3-L27-B9
A3-L27-B10
A3-L27-B11
A3-L27-B12
A3-L27-B13
A3-L28-B1
A3-L28-B2
A3-L28-B3
A3-L28-B4
A3-L28-B5
A3-L28-B6
A3-L28-B7
A3-L28-B8
A3-L28-B9
A3-L28-B10
A3-L28-B11
A3-L28-B12
A3-L28-B13
A3-L29-B1
A3-L29-B2
A3-L29-B3
A3-L29-B4
A3-L29-B5
A3-L29-B6
A3-L29-B7
A3-L29-B8
A3-L29-B9
A3-L29-B10
A3-L29-B11
A3-L29-B12
A3-L29-B13
A3-L30-B1
A3-L30-B2
A3-L30-B3
A3-L30-B4
A3-L30-B5
A3-L30-B6
A3-L30-B7
A3-L30-B8
A3-L30-B9
A3-L30-B10
A3-L30-B11
A3-L30-B12
A3-L30-B13
A3-L31-B1
A3-L31-B2
A3-L31-B3
A3-L31-B4
A3-L31-B5
A3-L31-B6
A3-L31-B7
A3-L31-B8
A3-L31-B9
A3-L31-B10
A3-L31-B11
A3-L31-B12
A3-L31-B13
A3-L32-B1
A3-L32-B2
A3-L32-B3
A3-L32-B7
A3-L32-B8
A3-L32-B9
A3-L32-B11
A3-L32-B13
A3-L33-B1
A3-L33-B2
A3-L33-B3
A3-L33-B4
A3-L33-B5
A3-L33-B6
A3-L33-B7
A3-L33-B8
A3-L33-B9
A3-L33-B10
A3-L33-B11
A3-L33-B12
A3-L33-B13
A3-L34-B1
A3-L34-B2
A3-L34-B3
A3-L34-B7
A3-L34-B8
A3-L34-B9
A3-L34-B11
A3-L34-B13
A3-L35-B1
A3-L35-B2
A3-L35-B3
A3-L35-B4
A3-L35-B5
A3-L35-B6
A3-L35-B7
A3-L35-B8
A3-L35-B9
A3-L35-B10
A3-L35-B11
A3-L35-B12
A3-L35-B13
A3-L36-B1
A3-L36-B2
A3-L36-B3
A3-L36-B4
A3-L36-B5
A3-L36-B6
A3-L36-B7
A3-L36-B8
A3-L36-B9
A3-L36-B10
A3-L36-B11
A3-L36-B12
A3-L36-B13
A3-L37-B1
A3-L37-B2
A3-L37-B3
A3-L37-B4
A3-L37-B5
A3-L37-B6
A3-L37-B7
A3-L37-B8
A3-L37-B9
A3-L37-B10
A3-L37-B11
A3-L37-B12
A3-L37-B13
A3-L38-B1
A3-L38-B2
A3-L38-B3
A3-L38-B4
A3-L38-B5
A3-L38-B6
A3-L38-B7
A3-L38-B8
A3-L38-B9
A3-L38-B10
A3-L38-B11
A3-L38-B12
A3-L38-B13
A3-L39-B1
A3-L39-B2
A3-L39-B3
A3-L39-B4
A3-L39-B5
A3-L39-B6
A3-L39-B7
A3-L39-B8
A3-L39-B9
A3-L39-B10
A3-L39-B11
A3-L39-B12
A3-L39-B13
A3-L40-B1
A3-L40-B2
A3-L40-B3
A3-L40-B4
A3-L40-B5
A3-L40-B6
A3-L40-B7
A3-L40-B8
A3-L40-B9
A3-L40-B10
A3-L40-B11
A3-L40-B12
A3-L40-B13
A3-L41-B1
A3-L41-B2
A3-L41-B3
A3-L41-B4
A3-L41-B5
A3-L41-B6
A3-L41-B7
A3-L41-B8
A3-L41-B9
A3-L41-B10
A3-L41-B11
A3-L41-B12
A3-L41-B13
A3-L42-B1
A3-L42-B2
A3-L42-B3
A3-L42-B4
A3-L42-B5
A3-L42-B6
A3-L42-B7
A3-L42-B8
A3-L42-B9
A3-L42-B10
A3-L42-B11
A3-L42-B12
A3-L42-B13
A3-L43-B1
A3-L43-B2
A3-L43-B3
A3-L43-B4
A3-L43-B5
A3-L43-B6
A3-L43-B7
A3-L43-B8
A3-L43-B9
A3-L43-B10
A3-L43-B11
A3-L43-B12
A3-L43-B13
A3-L44-B1
A3-L44-B2
A3-L44-B3
A3-L44-B7
A3-L44-B8
A3-L44-B9
A3-L44-B11
A3-L44-B13
A1-L20-B14
A1-L21-B14
A1-L22-B14
A1-L23-B14
A1-L24-B14
A1-L2-B14
A1-L3-B14
A1-L45-B14
A1-L20-B15
A1-L21-B15
A1-L22-B15
A1-L23-B15
A1-L24-B15
A1-L2-B15
A1-L3-B15
A1-L45-B15
A1-L20-B16
A1-L21-B16
A1-L22-B16
A1-L23-B16
A1-L24-B16
A1-L2-B16
A1-L3-B16
A1-L45-B16
A1-L20-B17
A1-L21-B17
A1-L22-B17
A1-L23-B17
A1-L24-B17
A1-L2-B17
A1-L3-B17
A1-L45-B17
A1-L20-B18
A1-L21-B18
A1-L22-B18
A1-L23-B18
A1-L24-B18
A1-L2-B18
A1-L3-B18
A1-L45-B18
A1-L20-B19
A1-L21-B19
A1-L22-B19
A1-L23-B19
A1-L24-B19
A1-L2-B19
A1-L3-B19
A1-L45-B19
A4-L46-B10
A4-L18-B10
A4-L19-B10
A4-L46-B15
A4-L18-B15
A4-L19-B15
A4-L46-B16
A4-L18-B16
A4-L19-B16
A4-L46-B6
A4-L18-B6
A4-L19-B6
A1-L45-B10
or a stereoisomer, mixture of stereoisomers, hydrate, solvate, isotopically enriched analog or pharmaceutically acceptable salt thereof.

1,505 more elements

Dependencies are inferred from the claim text.

Facts

Application: 17/096,743Filed 12 Nov 2020
Priority: 13 Nov 2019
Published: 15 Jul 2021
Term ends: Not estimatedThe source records don’t support an estimate.

Classification5 codes

C07D 237/32
Phthalazines: with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
C07J 43/003
Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopentahydrophenanthrene skeleton: not condensed
C07J 71/0047
Nitrogen only: at position 2
C07D
Heterocyclic compounds

Family

Application62/935,065Us provisional application · filed 13 Nov 2019
US 11,952,349 B2Related patent
US 2021/0214316 A1This patent

From the US filing history. Foreign family members aren’t listed.

Timeline

Citations

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Abstract

The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

A compound of Formula A-L-B, wherein:

A is A1, A2, A3, or A4, wherein:
A1 is
A2 is
A3 is
and
A4 is
L is L1, L2, L3, L4, L5, L6, L7, L8, L9, L10, L11, L12, L13, L14, L15, L16, L17, L18, L19, L20, L21, L22, L23, L24, L25, L26, L27, L28, L29, L30, L31, L32, L33, L34, L35, L36, L37, L38, L39, L40, L41, L42, L43, L44, L45, or L46, wherein:
L1 is
L2 is
L3 is
L4 is
L5 is
L6 is
L7 is
L8 is
L9 is
L10 is
L11 is
L12 is
L13 is
L14 is
L15 is
L16 is
L17 is
L18 is
L19 is
L20 is
L21 is
L22 is
L23 is
L24 is
L25 is
L26 is
L27 is
L28 is
L29 is
L30 is
L31 is
L32 is
L33 is
L34 is
L35 is
L36 is
L37 is
L38 is
L39 is
L40 is
L41 is
L42 is
L43 is
L44 is
L45 is
and
L46 is
and;
B is B1, B2, B3, B4, B5, B6, B7, B8, B9, B10, B11, B12, B13, B14, B15, B16, B17, B18, or B19, wherein:
B1 is
B2 is
B3 is
B4 is
B5 is
B6 is
B7 is
B8 is
B9 is
B10 is
B11 is
B12 is
B13 is
B14 is
B15 is
B16 is
B17 is
B18 is
and
B19 is
and further wherein the “*” in each A and L moiety denotes a covalent bond therebetween, and the wavy line in each L and B denotes a covalent bond therebetween;
wherein the compound of Formula A-L-B is selected from:
A1-L1-B1
A1-L1-B2
A1-L1-B3
A1-L1-B4
A1-L1-B5
A1-L1-B6
A1-L1-B7
A1-L1-B8
A1-L1-B9
A1-L1-B10
A1-L1-B11
A1-L1-B12
A1-L1-B13
A1-L2-B1
A1-L2-B2
A1-L2-B3
A1-L2-B4
A1-L2-B5
A1-L2-B6
A1-L2-B7
A1-L2-B8
A1-L2-B9
A1-L2-B10
A1-L2-B11
A1-L2-B12
A1-L2-B13
A1-L3-B1
A1-L3-B2
A1-L3-B3
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A3-L2-B6
A3-L2-B7
A3-L2-B8
A3-L2-B9
A3-L2-B10
A3-L2-B11
A3-L2-B12
A3-L2-B13
A3-L3-B1
A3-L3-B2
A3-L3-B3
A3-L3-B4
A3-L3-B5
A3-L3-B6
A3-L3-B7
A3-L3-B8
A3-L3-B9
A3-L3-B10
A3-L3-B11
A3-L3-B12
A3-L3-B13
A3-L4-B1
A3-L4-B2
A3-L4-B3
A3-L4-B4
A3-L4-B5
A3-L4-B6
A3-L4-B7
A3-L4-B8
A3-L4-B9
A3-L4-B10
A3-L4-B11
A3-L4-B12
A3-L4-B13
A3-L5-B1
A3-L5-B2
A3-L5-B3
A3-L5-B4
A3-L5-B5
A3-L5-B6
A3-L5-B7
A3-L5-B8
A3-L5-B9
A3-L5-B10
A3-L5-B11
A3-L5-B12
A3-L5-B13
A3-L6-B1
A3-L6-B2
A3-L6-B3
A3-L6-B4
A3-L6-B5
A3-L6-B6
A3-L6-B7
A3-L6-B8
A3-L6-B9
A3-L6-B10
A3-L6-B11
A3-L6-B12
A3-L6-B13
A3-L7-B1
A3-L7-B2
A3-L7-B3
A3-L7-B4
A3-L7-B5
A3-L7-B6
A3-L7-B7
A3-L7-B8
A3-L7-B9
A3-L7-B10
A3-L7-B11
A3-L7-B12
A3-L7-B13
A3-L8-B1
A3-L8-B2
A3-L8-B3
A3-L8-B4
A3-L8-B5
A3-L8-B6
A3-L8-B7
A3-L8-B8
A3-L8-B9
A3-L8-B10
A3-L8-B11
A3-L8-B12
A3-L8-B13
A3-L9-B1
A3-L9-B2
A3-L9-B3
A3-L9-B7
A3-L9-B8
A3-L9-B9
A3-L9-B11
A3-L9-B13
A3-L10-B1
A3-L10-B2
A3-L10-B3
A3-L10-B4
A3-L10-B5
A3-L10-B6
A3-L10-B7
A3-L10-B8
A3-L10-B9
A3-L10-B10
A3-L10-B11
A3-L10-B12
A3-L10-B13
A3-L11-B1
A3-L11-B2
A3-L11-B3
A3-L11-B4
A3-L11-B5
A3-L11-B6
A3-L11-B7
A3-L11-B8
A3-L11-B9
A3-L11-B10
A3-L11-B11
A3-L11-B12
A3-L11-B13
A3-L12-B1
A3-L12-B2
A3-L12-B3
A3-L12-B7
A3-L12-B8
A3-L12-B9
A3-L12-B11
A3-L12-B13
A3-L13-B1
A3-L13-B2
A3-L13-B3
A3-L13-B4
A3-L13-B5
A3-L13-B6
A3-L13-B7
A3-L13-B8
A3-L13-B9
A3-L13-B10
A3-L13-B11
A3-L13-B12
A3-L13-B13
A3-L14-B1
A3-L14-B2
A3-L14-B3
A3-L14-B4
A3-L14-B5
A3-L14-B6
A3-L14-B7
A3-L14-B8
A3-L14-B9
A3-L14-B10
A3-L14-B11
A3-L14-B12
A3-L14-B13
A3-L15-B1
A3-L15-B2
A3-L15-B3
A3-L15-B4
A3-L15-B5
A3-L15-B6
A3-L15-B7
A3-L15-B8
A3-L15-B9
A3-L15-B10
A3-L15-B11
A3-L15-B12
A3-L15-B13
A3-L16-B1
A3-L16-B2
A3-L16-B3
A3-L16-B4
A3-L16-B5
A3-L16-B6
A3-L16-B7
A3-L16-B8
A3-L16-B9
A3-L16-B10
A3-L16-B11
A3-L16-B12
A3-L16-B13
A3-L17-B1
A3-L17-B2
A3-L17-B3
A3-L17-B7
A3-L17-B8
A3-L17-B9
A3-L17-B11
A3-L17-B13
A3-L18-B1
A3-L18-B2
A3-L18-B3
A3-L18-B4
A3-L18-B5
A3-L18-B6
A3-L18-B7
A3-L18-B8
A3-L18-B9
A3-L18-B10
A3-L18-B11
A3-L18-B12
A3-L18-B13
A3-L19-B1
A3-L19-B2
A3-L19-B3
A3-L19-B4
A3-L19-B5
A3-L19-B6
A3-L19-B7
A3-L19-B8
A3-L19-B9
A3-L19-B10
A3-L19-B11
A3-L19-B12
A3-L19-B13
A3-L20-B1
A3-L20-B2
A3-L20-B3
A3-L20-B4
A3-L20-B5
A3-L20-B6
A3-L20-B7
A3-L20-B8
A3-L20-B9
A3-L20-B10
A3-L20-B11
A3-L20-B12
A3-L20-B13
A3-L21-B1
A3-L21-B2
A3-L21-B3
A3-L21-B4
A3-L21-B5
A3-L21-B6
A3-L21-B7
A3-L21-B8
A3-L21-B9
A3-L21-B10
A3-L21-B11
A3-L21-B12
A3-L21-B13
A3-L22-B1
A3-L22-B2
A3-L22-B3
A3-L22-B4
A3-L22-B5
A3-L22-B6
A3-L22-B7
A3-L22-B8
A3-L22-B9
A3-L22-B10
A3-L22-B11
A3-L22-B12
A3-L22-B13
A3-L23-B1
A3-L23-B2
A3-L23-B3
A3-L23-B4
A3-L23-B5
A3-L23-B6
A3-L23-B7
A3-L23-B8
A3-L23-B9
A3-L23-B10
A3-L23-B11
A3-L23-B12
A3-L23-B13
A3-L24-B1
A3-L24-B2
A3-L24-B3
A3-L24-B4
A3-L24-B5
A3-L24-B6
A3-L24-B7
A3-L24-B8
A3-L24-B9
A3-L24-B10
A3-L24-B11
A3-L24-B12
A3-L24-B13
A3-L25-B1
A3-L25-B2
A3-L25-B3
A3-L25-B4
A3-L25-B5
A3-L25-B6
A3-L25-B7
A3-L25-B8
A3-L25-B9
A3-L25-B10
A3-L25-B11
A3-L25-B12
A3-L25-B13
A3-L26-B1
A3-L26-B2
A3-L26-B3
A3-L26-B4
A3-L26-B5
A3-L26-B6
A3-L26-B7
A3-L26-B8
A3-L26-B9
A3-L26-B10
A3-L26-B11
A3-L26-B12
A3-L26-B13
A3-L27-B1
A3-L27-B2
A3-L27-B3
A3-L27-B4
A3-L27-B5
A3-L27-B6
A3-L27-B7
A3-L27-B8
A3-L27-B9
A3-L27-B10
A3-L27-B11
A3-L27-B12
A3-L27-B13
A3-L28-B1
A3-L28-B2
A3-L28-B3
A3-L28-B4
A3-L28-B5
A3-L28-B6
A3-L28-B7
A3-L28-B8
A3-L28-B9
A3-L28-B10
A3-L28-B11
A3-L28-B12
A3-L28-B13
A3-L29-B1
A3-L29-B2
A3-L29-B3
A3-L29-B4
A3-L29-B5
A3-L29-B6
A3-L29-B7
A3-L29-B8
A3-L29-B9
A3-L29-B10
A3-L29-B11
A3-L29-B12
A3-L29-B13
A3-L30-B1
A3-L30-B2
A3-L30-B3
A3-L30-B4
A3-L30-B5
A3-L30-B6
A3-L30-B7
A3-L30-B8
A3-L30-B9
A3-L30-B10
A3-L30-B11
A3-L30-B12
A3-L30-B13
A3-L31-B1
A3-L31-B2
A3-L31-B3
A3-L31-B4
A3-L31-B5
A3-L31-B6
A3-L31-B7
A3-L31-B8
A3-L31-B9
A3-L31-B10
A3-L31-B11
A3-L31-B12
A3-L31-B13
A3-L32-B1
A3-L32-B2
A3-L32-B3
A3-L32-B7
A3-L32-B8
A3-L32-B9
A3-L32-B11
A3-L32-B13
A3-L33-B1
A3-L33-B2
A3-L33-B3
A3-L33-B4
A3-L33-B5
A3-L33-B6
A3-L33-B7
A3-L33-B8
A3-L33-B9
A3-L33-B10
A3-L33-B11
A3-L33-B12
A3-L33-B13
A3-L34-B1
A3-L34-B2
A3-L34-B3
A3-L34-B7
A3-L34-B8
A3-L34-B9
A3-L34-B11
A3-L34-B13
A3-L35-B1
A3-L35-B2
A3-L35-B3
A3-L35-B4
A3-L35-B5
A3-L35-B6
A3-L35-B7
A3-L35-B8
A3-L35-B9
A3-L35-B10
A3-L35-B11
A3-L35-B12
A3-L35-B13
A3-L36-B1
A3-L36-B2
A3-L36-B3
A3-L36-B4
A3-L36-B5
A3-L36-B6
A3-L36-B7
A3-L36-B8
A3-L36-B9
A3-L36-B10
A3-L36-B11
A3-L36-B12
A3-L36-B13
A3-L37-B1
A3-L37-B2
A3-L37-B3
A3-L37-B4
A3-L37-B5
A3-L37-B6
A3-L37-B7
A3-L37-B8
A3-L37-B9
A3-L37-B10
A3-L37-B11
A3-L37-B12
A3-L37-B13
A3-L38-B1
A3-L38-B2
A3-L38-B3
A3-L38-B4
A3-L38-B5
A3-L38-B6
A3-L38-B7
A3-L38-B8
A3-L38-B9
A3-L38-B10
A3-L38-B11
A3-L38-B12
A3-L38-B13
A3-L39-B1
A3-L39-B2
A3-L39-B3
A3-L39-B4
A3-L39-B5
A3-L39-B6
A3-L39-B7
A3-L39-B8
A3-L39-B9
A3-L39-B10
A3-L39-B11
A3-L39-B12
A3-L39-B13
A3-L40-B1
A3-L40-B2
A3-L40-B3
A3-L40-B4
A3-L40-B5
A3-L40-B6
A3-L40-B7
A3-L40-B8
A3-L40-B9
A3-L40-B10
A3-L40-B11
A3-L40-B12
A3-L40-B13
A3-L41-B1
A3-L41-B2
A3-L41-B3
A3-L41-B4
A3-L41-B5
A3-L41-B6
A3-L41-B7
A3-L41-B8
A3-L41-B9
A3-L41-B10
A3-L41-B11
A3-L41-B12
A3-L41-B13
A3-L42-B1
A3-L42-B2
A3-L42-B3
A3-L42-B4
A3-L42-B5
A3-L42-B6
A3-L42-B7
A3-L42-B8
A3-L42-B9
A3-L42-B10
A3-L42-B11
A3-L42-B12
A3-L42-B13
A3-L43-B1
A3-L43-B2
A3-L43-B3
A3-L43-B4
A3-L43-B5
A3-L43-B6
A3-L43-B7
A3-L43-B8
A3-L43-B9
A3-L43-B10
A3-L43-B11
A3-L43-B12
A3-L43-B13
A3-L44-B1
A3-L44-B2
A3-L44-B3
A3-L44-B7
A3-L44-B8
A3-L44-B9
A3-L44-B11
A3-L44-B13
A1-L20-B14
A1-L21-B14
A1-L22-B14
A1-L23-B14
A1-L24-B14
A1-L2-B14
A1-L3-B14
A1-L45-B14
A1-L20-B15
A1-L21-B15
A1-L22-B15
A1-L23-B15
A1-L24-B15
A1-L2-B15
A1-L3-B15
A1-L45-B15
A1-L20-B16
A1-L21-B16
A1-L22-B16
A1-L23-B16
A1-L24-B16
A1-L2-B16
A1-L3-B16
A1-L45-B16
A1-L20-B17
A1-L21-B17
A1-L22-B17
A1-L23-B17
A1-L24-B17
A1-L2-B17
A1-L3-B17
A1-L45-B17
A1-L20-B18
A1-L21-B18
A1-L22-B18
A1-L23-B18
A1-L24-B18
A1-L2-B18
A1-L3-B18
A1-L45-B18
A1-L20-B19
A1-L21-B19
A1-L22-B19
A1-L23-B19
A1-L24-B19
A1-L2-B19
A1-L3-B19
A1-L45-B19
A4-L46-B10
A4-L18-B10
A4-L19-B10
A4-L46-B15
A4-L18-B15
A4-L19-B15
A4-L46-B16
A4-L18-B16
A4-L19-B16
A4-L46-B6
A4-L18-B6
A4-L19-B6
A1-L45-B10
or a stereoisomer, mixture of stereoisomers, hydrate, solvate, isotopically enriched analog or pharmaceutically acceptable salt thereof.

1,505 more elements

Facts

Application

17/096,743Filed 12 Nov 2020

Priority

13 Nov 2019

Published

15 Jul 2021

Term ends

Not estimatedThe source records don’t support an estimate.

Classification5 codes

C07D 237/32
Phthalazines: with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
C07J 43/003
Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopentahydrophenanthrene skeleton: not condensed
C07J 71/0047
Nitrogen only: at position 2
C07D
Heterocyclic compounds