Parasite vaccine
AssigneesThe Walter and Eliza Hall Instiitute of Medical Research, The University of Melbourne
InventorsChris TONKIN, Alessandro UBOLDI, Malcolm MCCONVILLE, Martin BLUME
Life of this patent
Estimating the term…
Abstract
The present disclosure provides mutant parasites, in particular protozoan parasites comprising a mutation of the trehalose-6-phosphate synthase/6-phosphate phosphatase (TPS/TPP)-like gene of Toxoplasma gondii (herein referred to as ‘Toxoplasma’) or a homologue thereof as well as vaccines comprising same.
Claims27
An isolated mutant protozoan parasite wherein the mutant is attenuated when grown or cultured in glucose-containing medium but not attenuated when grown or cultured in glucose-free medium and wherein said attenuation results from the uncontrolled accumulation of starch-like amylopectin stores when grown in glucose-containing medium.
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
A method for vaccinating an animal against toxoplasmosis without concomitant oocyst shedding or of preventing toxoplasmosis in an animal, the method comprising administering to the animal.
Dependencies are inferred from the claim text.