Methods of using water-soluble inorganic compounds for implants
AssigneeOrthomedex LLC
InventorJames A. WALLS
Life of this patent
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Abstract
A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-soluble inorganic material with at least one poorly-water-soluble or biodegradable matrix material. The matrix material, after it is mixed with the water-soluble inorganic material, is placed into the patient in proximity to tissue so that the water-soluble inorganic material dissolves at a predetermined rate to generate biologically desirable voids in the matrix material into which bone or other tissue can then grow.
Claims21
1-199. (canceled)
A bone cement comprising a poorly water-soluble bioactive implantable thermoplastic matrix material and, mixed with the matrix material, at least one type of bioactive glass particles having a selected particle size, a selected particle shape and a selected(particle dissolution rate, wherein once placed in proximity to tissue as an implant or with a separate implant, bodily fluids gradually dissolve the bioactive glass particles to provide an effective amount of at least one non-antibiotic antimicrobial agent.
A method for reducing risk of surgical site and implant infection, the method comprising:
- mixing a poorly water-soluble bioactive implantable thermoplastic matrix material with at least one type of bioactive glass particles having a selected particle size, a selected particle shape and a selected particle dissolution rate to form a mixture;
- and
- placing the mixture in proximity to tissue as an implant or with a separate implant, whereby bodily fluids gradually dissolve the bioactive glass particles to provide an effective amount of at least one non-antibiotic antimicrobial agent.
Dependencies are inferred from the claim text.