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US 2021/0205477 A1Published application
Methods for increasing platelet count by inhibiting biliverdin ixbeta reductase
AssigneeThe Research Foundation for The State University of New York
InventorsWadie F. BAHOU, Song WU
Life of this patent
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Abstract
The present disclosure provides methods of treating a human having a disease or disorder that would benefit from increasing platelet counts. The method involves inhibiting the enzyme activity of biliverdin IXβ reductase (BLVRB) activity or inhibiting the expression of BLVRB gene.
Claims16
-20. (canceled)
A method of treating a subject having a disease or disorder that would benefit from increasing platelet counts, the method comprising:
- administering to the subject therapeutically effective amount of an agent that inhibits biliverdin IXβ reductase (BLVRB) enzymatic activity and increases the platelet count of the subject.
Dependencies are inferred from the claim text.