Anti-cancer agent
AssigneeUniversity of Wollongong
InventorsCarolyn Therese Dillon, Judith Anne Carrall
Life of this patent
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Abstract
An anti-cancer agent is provided comprising a tumour homing peptide having, or having been modified to present, two cysteine residues, with an arsenic atom between, such that the tumour homing peptide cyclises to give an arsenic-containing anti-cancer agent. This allows for selection of an appropriate tumour homing peptide for treatment of a given cancer whereby the subsequent agent provides for a more targeted delivery of arsenic to the tumour microenvironment.
Claims25
An anti-cancer agent comprising a cyclised tumour homing peptide having an arsenic atom bonded to two cysteine residues.
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A process for producing an anti-cancer agent including the steps of:
- (a) contacting a tumour homing peptide comprising two cysteine residues with an arsenic compound;
- and
- (b) allowing the arsenic to become bound to each of the two cysteine residues to form a cyclised tumour homing peptide comprising a bound arsenic atom;
- to thereby produce the anti-cancer agent.
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Dependencies are inferred from the claim text.