Dexamethasone prodrug compositions and uses thereof
AssigneeRipple Therapeutics Corporation
InventorsIan Charles PARRAG, Matthew Alexander John STATHAM, Kyle BATTISTON, Dimitra LOUKA, Hans Christian FISCHER, J. Paul SANTERRE, Wendy Alison NAIMARK, Roseita Esfand
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Abstract
The disclosure features dexamethasone prodrug dimers of dexamethasone and pharmaceutical compositions thereof useful for, e.g., the extended release of a drug and for the treatment of a disease or condition.
Claims21
1-30. (canceled)
A coating comprising a compound having a structure represented by formula (I):
- wherein:
- n is an integer from 1 to 6,
- or a pharmaceutically salt or solvate thereof.
A method of treating inflammation in a subject, the method comprising administering to the subject an implantable device comprising a coating in an amount sufficient to treat inflammation in the subject, wherein the coating comprises a compound having a structure represented by formula (I):
- wherein:
- n is an integer from 1 to 6,
- or a pharmaceutically salt or solvate thereof.
Dependencies are inferred from the claim text.