Receptor response modulation method, and measuring device using receptor response modulation
AssigneeNational Institute for Materials Science
InventorsKosuke MINAMI, Gaku IMAMURA, Kota SHIBA, Genki YOSHIKAWA
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Abstract
In an analysis of a fluid component using a nanomechanical sensor covered with a receptor, the same receptor is caused to express different response characteristics. In a measuring system of analyzing a response when a sample gas and a purge gas are supplied to a nanomechanical sensor while switching the sample gas and the purge gas, a gas (external gas) different from both gases is mixed into a gas channel and supplied to the sensor for measurement. Since a response characteristic of a receptor is modulated by mixing of the external gas, the object described above is achieved.
Claims12
A receptor response modulation method comprising
- a step of supplying a fluid to be measured that contains a substance to be measured and may contain a first fluid as an optional component, and a second fluid that does not contain the substance to be measured to a nanomechanical sensor having a receptor on a surface thereof while switching the fluid to be measured and the second fluid,
- a step of mixing a third fluid different from the first fluid and the second fluid into at least one of the fluid to be measured and the second fluid on a flow channel through which the fluid to be measured and the second fluid are sent to the nanomechanical sensor, and
- a step of performing measurement of the substance to be measured based on an output signal obtained from the nanomechanical sensor in which a response characteristic of the receptor has been modulated by the mixing of the third fluid.
A measuring device using modulation of a receptor response by a third fluid, the measuring device comprising
- a nanomechanical sensor having a receptor on a surface thereof,
- a fluid supplying system of supplying a fluid to be measured that contains a substance to be measured and may contain a first fluid as an optional component, and a second fluid that does not contain the substance to be measured to the nanomechanical sensor while switching the fluid to be measured and the second fluid, and
- a third fluid mixing system of mixing the third fluid different from the first fluid and the second fluid into at least one of the fluid to be measured and the second fluid, wherein
- measurement of the substance to be measured is performed based on an output signal obtained from the nanomechanical sensor in which a response characteristic of the receptor has been modulated by the mixing of the third fluid.
Dependencies are inferred from the claim text.