Anti-vamp2 antibody for inhibiting snare complex and use thereof

An anti-VAMP2 antibody or antigen-binding fragment thereof comprising:

• a light chain variable region comprising a light chain CDR1 comprising an amino acid sequence represented by SEQ ID NO:
• 1, a light chain CDR2 comprising an amino acid sequence represented by SEQ ID NO:
• 2 and a light chain CDR3 comprising an amino acid sequence represented by SEQ ID NO:
• 3;
• and
• a heavy chain variable region comprising a heavy chain CDR1 comprising an amino acid sequence represented by SEQ ID NO:
• 4, a heavy chain CDR2 comprising an amino acid sequence represented by SEQ ID NO:
• 5, and a heavy chain CDR3 comprising an amino acid sequence represented by SEQ ID NO:
• 6.