Compounds for the degradation of brd9 or mth1

A compound selected from:

• or a pharmaceutically acceptable salt thereof;
• wherein:
• Degron is selected from:
• D1 is selected from:
• TL1 is a moiety that binds to BRD9 selected from
• TL2 is a moiety that binds to BRD9 selected from
• L1 is selected from:
• X1, X2, X3, and X4 are independently selected from CR4 and N, wherein no more than two of X1, X2, X3, and X4 may be selected to be N;
• X5 and X6 are independently selected from CR4 and N;
• Z2 and Z3 are selected from —CH2— and —C(O)— wherein at least one of Z2 and Z3 is —C(O)—;
• n is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10;
• o is 1, 2, 3, or 4;
• each Q is independently 0, S, or NR5;
• R1 is hydrogen or C1-C6 alkyl;
• R2, R3, and R6 are independently selected from hydrogen and C1-C6alkyl;
• each R4 is independently selected from hydrogen, halogen, hydroxyl, C1-C6alkyl, C1-C6alkoxy, and C1-C6haloalkyl;
• each R5 is independently hydrogen, C1-C6alkyl, or —C(O)alkyl;
• R7 is selected from halogen, hydrogen, C1-C6alkyl, C1-C6alkoxy, and C1-C6haloalkyl;
• each R8 is independently selected from hydrogen, C1-C6alkyl, and C1-C6haloalkyl;
• or two R8 groups together with the carbon to which they are attached form a cyclopropyl group;
• L2 is selected from:
• bond
• L3 is selected from bond, aryl, heterocycle, heteroaryl,
• m is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10;
• R10 is selected from C1-C6alkyl, cycloalkyl, heterocycle, heteroaryl, —C1-C6alkyl-aryl, and aryl;
• each of which R10 group is optionally substituted with 1, 2, 3, or 4 substituents independently selected from R11;
• R11 is selected from hydrogen, halogen, —NR1R14, —OR11, C1-C6alkyl, C1-C6haloalkyl, —SO2NR1R14, —SO2OR14, —SONR1R14, and —S(O)OR14;
• each R12 is independently selected from hydrogen, halogen, C1-C6alkyl, C1-C6alkoxy, and C1-C6haloalkyl;
• R13 is selected from hydrogen, C1-C6alkyl, cycloalkyl, and heterocycle;
• each of which cycloalkyl and heterocycle is optionally substituted with 1, 2, 3, or 4 substituents independently selected from R11;
• and
• each instance of R14 is independently selected from hydrogen, C1-C6alkyl, C(O)alkyl, and C(O)NR1R1.