Gas5 binding compounds, formulations, and uses thereof

A pharmaceutical formulation comprising:

• a compound having a structure according to Formula 1
• wherein R1 is a methyl, an isobutane, a phenyl, an indole, or a butanamine,
• wherein R2 is an ethylbenzene, an ethylcyclohexane, an isopentane, a phenyl, a propanamine, or a methylcyclopropane,
• wherein R3 is a methylcyclopropane, a propionic acid, an ethylbenzene, or a propanamine
• wherein R4 is a butanamine, a propionic acid, or a phenyl,
• wherein R5 is a methylcyclopropane, a propionic acid, or an ethylbenzene,
• wherein R6 is a phenyl, a propionic acid, an isobutene, and
• wherein R7 is a phenyl, a propionic acid, a butanamine, or a methyl;
• and
• a pharmaceutically acceptable carrier.

A method of treating a disease or a disorder or a symptom thereof in a subject in need thereof, the method comprising:

• administering an amount of a compound having a structure according to Formula 1
• wherein R1 is a methyl, an isobutane, a phenyl, an indole, or a butanamine,
• wherein R2 is an ethylbenzene, an ethylcyclohexane, an isopentane, a phenyl, a propanamine, or a methylcyclopropane,
• wherein R3 is a methylcyclopropane, a propionic acid, an ethylbenzene, or a propanamine
• wherein R4 is a butanamine, a propionic acid, or a phenyl,
• wherein R5 is a methylcyclopropane, a propionic acid, or an ethylbenzene,
• wherein R6 is a phenyl, a propionic acid, an isobutene, and
• wherein R7 is a phenyl, a propionic acid, a butanamine, or a methyl
• or a pharmaceutical formulation thereof to the subject in need thereof.