Drug Eluting Balloon
AssigneeOrbusNeich Medical, Inc.
InventorsRobert J. Cottone, Stephen Rowland
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Abstract
The present invention is an inflatable balloon which is enclosed by an expandable cover which becomes increasingly porous/permeable during expansion. The balloon is coated or enclosed with a matrix which contains a pharmaceutically active agent. During expansion of the balloon, the pharmaceutically active agent is released or extruded through the expandable cover into a body cavity such as an artery or vein. The present invention also provides for a method of treating a disease or condition by delivering the inflatable balloon to a particular body cavity.
Claims85
An inflatable balloon comprising a coating, wherein the coating comprises at least one pharmaceutical agent, wherein the balloon is enclosed by an expandable cover, and wherein permeability of the expandable cover in an expanded state is greater than the permeability of the expandable cover in an unexpanded state.
A method of treating a disease, comprising inserting an inflatable balloon into a body cavity, balloon comprising a coating, wherein the coating comprises at least one pharmaceutical agent, wherein the balloon is enclosed by an expandable cover, and wherein permeability of the expandable cover in an expanded state is greater than the permeability of the expandable cover in an unexpanded state.
An inflatable balloon comprising a coating, wherein the coating comprises at least one pharmaceutical agent, wherein the balloon is enclosed by an expandable cover, and wherein porosity of the expandable cover in an expanded state is greater than the porosity of the expandable cover when it is in an unexpanded state.
An inflatable balloon comprising at least one inflatable body portion and at least one pharmaceutically active agent that, during use, is released from said inflatable body portion, wherein said inflatable body portion is covered by a cover that is permeable to said pharmaceutically active agent at least when said inflatable body portion is in an expanded state, and wherein said pharmaceutically active agent resides in between said body portion and said cover.
Catheter comprising the inflatable balloon according to anyone of the preceding claims.
Dependencies are inferred from the claim text.