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US 2021/0196818 A1Published application
Vaccines with interleukin-33 as an adjuvant
AssigneeThe Trustees of the University of Pennsylvania
InventorsDavid Weiner, Daniel Villarreal, Matthew Morrow, Jian Yan
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Abstract
Disclosed herein is a vaccine comprising an antigen and IL-33. Also disclosed herein is a method for increasing an immune response in a subject in need thereof. Further disclosed herein is a method for treating cancer in a subject in need thereof. The methods may comprise administering the vaccine to the subject.
Claims33
A vaccine comprising an antigen and IL-33.
A nucleic acid molecule comprising one or more nucleotide sequences selected from the group consisting of:
- SEQ ID NO:1, SEQ ID NO:3, a nucleotide sequence that is 95% identical or greater to SEQ ID NO:1, a nucleotide sequence that is 95% identical or greater to SEQ ID NO:3, and any combination thereof.
Dependencies are inferred from the claim text.