Immunoregulatory molecules and uses therefor
AssigneeThe Frances Crick Institute Limited
InventorsMaria Carola GARCIA DE VINUESA DE LA CONCHA, Paula Carolina Cecilia GONZALEZ-FIGUEROA
Life of this patent
Estimating the term…
Abstract
Disclosed are agents and methods for treating unwanted or deleterious immune responses. More particularly, the present invention discloses neuritin agents for use in inhibiting plasma cell (PC) differentiation, reducing the number of autoreactive B cells, treating, or inhibiting the development or progression of, autoreactive B cell disorders including B cell-mediated autoimmune diseases and IgE-mediated disorders and of monoclonal gammopathies and PC dyscrasias.
Claims25
A method for inhibiting plasma cell (PC) differentiation in a subject, the method comprising, consisting or consisting essentially of contacting a B cell of the subject with a neuritin polypeptide, to thereby inhibit PC differentiation in the subject.
(canceled)
(canceled)
-54. (canceled)
(canceled)
-60. (canceled)
Dependencies are inferred from the claim text.