Peptides for use in promoting transport of glucose
AssigneeNuritas Limited
InventorsNora KHALDI, Cyril LOPEZ
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Abstract
A natural glucose transport promoting peptide comprising a glucose transport promoting fragment of a protein selected from SEQ ID NOs: 1 to 6, and a composition comprising a plurality of glucose transport promoting peptides, is described. Also disclosed is the use of the peptides and compositions in improving muscle status in a mammal, especially promoting recovery of muscle following exercise or enhancing physical performance.
Claims8
-10. (canceled)
A comestible powder composition comprising a peptide that is up to 50 amino acids and comprises the amino acid SEQ ID NO:
- 154, or a glucose transport promoting variant of amino acid SEQ ID NO:
- 154, having 1 or 2 amino acid alterations compared with SEQ ID NO:
- 154, in which the or each amino acid alteration is selected from insertion, addition, deletion and substitution of an amino acid.
The comestible powder composition of claim 1, wherein the variant has 1 amino acid deletion compared with SEQ ID NO:
- 154.
The comestible powder composition of claim 1, wherein the comestible powder is a nutritional supplement or a food additive.
A method of improving glycaemic management in a mammal, the method comprising, a step of orally administering to the mammal a comestible powder of claim 1, in which glycaemic management in the mammal is improved by one or more of lowering plasma blood glucose levels, treating or preventing hyperglycaemia, increasing post prandial insulin secretion, regulating glucose homeostasis and reducing or attenuating insulin resistance.
Dependencies are inferred from the claim text.