Methods to reduce complications of intra-articular steroid
AssigneesTaiwan Liposome Co., Ltd., Tlc Biopharmaceuticals, Inc.
InventorsSheue-Fang SHIH, Po-Chun CHANG, Ming-Ju WU
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Abstract
Provided are methods of treating joint pain, comprising administering to a subject in need of joint pain treatment an effective amount of a pharmaceutical composition comprising a lipid mixture comprising one or more lipids; and an effective amount of an intra-articular steroid or a pharmaceutically acceptable salt thereof, wherein the therapeutic efficacy of the intra-articular steroid is sustained but the side effects associated with the intra-articular steroid are reduced.
Claims17
1-15. (canceled)
A method of treating joint pain and reducing side effects induced by an intra-articular (IA) steroid, comprising administering to a subject in need of treatment for joint pain an effective amount of a pharmaceutical composition comprising
- (a) a lipid mixture comprising one or more lipids;
- and
- (b) an effective amount of the IA steroid or a pharmaceutically acceptable salt thereof, wherein at least one side effect associated with the IA steroid in the subject is reduced compared to the side effect in a subject administered with the IA steroid without the lipid mixture.
A fixed dose composition for treating joint pain or inflammation, wherein the pharmaceutical composition comprises:
- (a) a lipid mixture comprising one or more lipids;
- and
- (b) an IA steroid or a pharmaceutically acceptable salt thereof,
- wherein the IA steroid is dexamethasone sodium phosphate at a dose ranging from 10 mg to 14 mg.
Dependencies are inferred from the claim text.