Implants for bone and cartilage repair
AssigneeCollagen Matrix, Inc.
InventorsShu-Tung Li, Hui-Chen Chen, Debbie Yuen
Life of this patent
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Abstract
An implant for the repair of bone and cartilage that includes a cell conductive zone that contains biopolymeric fibers and an osteoconductive zone that contains biopolymeric fibers and calcium-containing mineral particles. The biopolymeric fibers from one zone overlap with the fibers in the other zone forming a stable physical and mechanical integration of the two zones, thus conferring in vivo stability to the implant.
Claims20
A biocompatible and bioresorbable implant having a physically and mechanically stable bi-phasic structure for the repair of bone and cartilage, comprising a cell conductive zone that contains a first matrix including first biopolymeric fibers, and an osteoconductive zone that contains a second matrix including second biopolymeric fibers and calcium-containing mineral particles, wherein the first biopolymeric fibers in the first matrix are derived from tendon or dermis, the cell conductive zone is free of calcium-containing mineral particles, the first biopolymeric fibers extend into the osteoconductive zone and overlap with the second biopolymeric fibers, and the cell conductive zone overlaps with and is in direct contact with the osteoconductive zone.
A biocompatible and bioresorbable implant for the repair of bone and cartilage, comprising a matrix that contains biopolymeric fibers, the matrix having a cell conductive zone and an osteoconductive zone, wherein the osteoconductive zone includes calcium-containing mineral particles, the cell conductive zone is free of calcium-containing mineral particles, the biopolymeric fibers extend from the cell conductive zone into the osteoconductive zone, the biopolymeric fibers are derived from tendon or dermis, and the cell conductive zone is in direct contact with the osteoconductive zone.
Dependencies are inferred from the claim text.