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US 2021/0179538 A1Published application
Method for producing 2-octylglycine ester having optical activity
AssigneeAminologics Co., Ltd.
InventorsIl Suk Byun, Jin Suk Lee, Won Sup Kim
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Abstract
A method for producing a 2-octylglycine ester having optical activity from a racemic 2-octyl-DL-glycine ester and, more particularly, to a method for producing a 2-octyl-L-glycine ester or a 2-octyl-D-glycine ester by using a chiral mandelic acid as an optical resolution agent.
Claims7
A method for producing a 2-octylglycine ester having optical activity, the 2-octylglycine ester being represented by Formula 1, characterized in that a 2-octyl-DL-glycine ester is reacted with a chiral mandelic acid represented by Formula 2 as a chiral resolving agent:
- wherein R is an alkyl group having 1 to 4 carbon atoms, and
- * is a chiral center;
- wherein X is hydrogen;
- a methoxy group;
- an alkyl group having 1 to 3 carbon atoms;
- fluorine;
- chlorine;
- bromine;
- or a cyano group, and
- * is a chiral center.
7 more elements
Dependencies are inferred from the claim text.